Blood Weekly
Susan Hasty, Publisher
Table of Contents . . . August 12th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Blood Weekly | Other Publications
Blood Banking - Medical equipment manufacturer expands blood bioarchiving system market
Blood Banking - System for collecting red blood cells better meets transfusion needs
Diagnostics - T. vaginalis infection in men detected by sampling multiple genitourinary sites
Pharmaceutical & Drug Development - Novel screening assay identifies antiviral compounds
Transplant Medicine - Extended hypothermic machine perfusion impedes liver graft survival
Acute Myeloid Leukemia - Gene profiles could improve AML diagnosis, provide insight on better treatments
Adverse Drug Effects - Breath carbon monoxide measures the effects of ribavirin on red blood cells
Air Pollution - Maximum levels of benzene found at traffic stops and gas stations in Mumbai city
Allergy & Immunology - IL-4/IL-13 downregulate paxillin expression in bronchial airway epithelial cells
Allergy & Immunology - Novel mechanism used by infectious agents subverts first line of host defense
Antimicrobial Resistance - MRSA and vancomycin-resistant enterococci associated with adverse outcomes
Antiretroviral Therapy - I50L is signature mutation for ATV resistance in treatment-naive HIV-1-infection
Antiretroviral Therapy - Stability and activity of ADAM NNRTIs improved
Apoptosis - Cytomegalovirus infection blocks apoptosis in cancer cells
Apoptosis - Nonylphenol induces apoptosis via Fas/FasL pathway by mimicking estrogen
Atrial Fibrillation - Anticoagulation in patients with atrial fibrillation is feasible
Bacterial Toxin - Clostridium sordellii lethal toxin maintained in multimeric protein complex
Blood Safety - West Nile prompts rethinking of blood donors
Breast Cancer - DNA methylation predicts hormonal/nonhormonal breast cancer therapy response
Breast Cancer - False-negatives for sentinel node positivity increase in breast cancer staging
Cancer Therapy - Antimutagenic activity of bifidobacteria vary with acid/bile treatment
Cancer Therapy - Fatigue may be due more to depression than chemotherapy side effects
Colon Cancer - Immunotoxin linked to monoclonal Ab or C5 cytotoxic against colon cancer cells
Complementary & Alternative Medicine - Curcumin induces apoptosis in lung cancer cells
Complementary & Alternative Medicine - Study of rice bran's effect on platelet aggregation sparks further research
Cryptococcosis - Organ-specific selection can occur during cryptococcosis
DNA Damage - UV-dependent alternative splicing uncouples p53 activity and PIG3 gene function
Detoxification - Dexmedetomidine facilitates opioid and benzodiazepine detoxification
Diabetes - Third-generation beta-blocker reduces side effects in diabetes type 2 patients
Diagnostics - Company to market noninvasive test for blood hematocrit
Diagnostics - Majority of ANCA-positive vasculitis patients present in summer and winter
Diagnostics - PCR primers amplify 65-kDa mannoprotein gene for identification of C. albicans
Diagnostics - Spiral CT scanning favorable for detection of small sized lung cancers
Facilities - Company adds dialysis facilities
Finance - Biopharma company increases series E preferred stock round by $30 million
Finance - Glycobiology company inks agreement to close on $5,000,000 of funding
Forensics - DNAPrint genomics enters distribution agreement
Genomics - Novel epidermal growth factor domain gene is expressed in endothelial cells
Genomics & Genetics - BMT for therapy-related AML in acute RB associated with 13q deletion syndrome
Graft-versus-Host Disease - orBec trial enrollment complete for GvHD
HIV/AIDS & Heart Disease - CABG for unstable angina does not effect CD4 cells and HIV viral load
HIV/AIDS Blood Safety - Nucleic acid testing for HIV-1 and HIV-2 increases safety of donated blood
HIV/AIDS Diagnostics - HIV-1 subtype G detected using Cobas ampliscreen test
HIV/AIDS Managed Care - Solid organ transplantation in HIV-infected patients feasible in era of HAART
HIV/AIDS Prevention - Foundation launches major initiative to prevent spread of HIV
HIV/AIDS Prognostics - T cell activation/maturation help predict treatment response in HIV infection
HIV/AIDS Research - Activated macrophage/microglial cells have neuroprotective role in HIV infection
HIV/AIDS Research - Activated naive B cells in HIV-1 infection down-regulate CXCR5 on their surface
HIV/AIDS Research - Anti-HIV activity found in peptides derived from SDF-1 C-terminal sequence
HIV/AIDS Research - Bidirectional SF2/ASF-/SRp40-dependent ESE regulates HIV-1 rev/env/vpu/nef mRNAs
HIV/AIDS Research - C-terminus alterations of HIV-1 vpr do not correlate to disease intensity
HIV/AIDS Research - Configurations of metallocyclams and relevance to anti-HIV activity elucidated
HIV/AIDS Research - HIV-1 RNA level in cervical secretions influenced by menstrual cycle
HIV/AIDS Research - HIV-1 genomes reside within actively transcribed host genes in resting CD4 cells
HIV/AIDS Research - ICAM-3 increases HIV-1 transcription and viral production
HIV/AIDS Research - Minor baseline HIV protease mutation predict 90M mutation at virological failure
HIV/AIDS Research - Nef enhances infectivity of HIV-1 particles produced in primary T cells
HIV/AIDS Research - Proteoglycans contribute to HIV-1 brain invasion
HIV/AIDS Research - SIN HIV-1-based vectors identify synthetic endothelial cell-specific promoters
Heart Failure - New pharmacological treatments for heart failure available
Heart Transplantation - VentrAssist pilot trial update
Hematology - A palindrome-flanked mitochondrial DNA deletion delineates Fanconi syndrome
Hematology - Effects of monocyte-stroma interactions on stem cells determined
Hematology - Soldiers' daughter thrives thanks to platelet donors
Hemophilia A - Support extended for study in prophylactic treatment of hemophilia A
Hepatitis - Assay proven to ID previously undedectable hepatitis B blood donations
Hepatitis B Virus - Novel cis-acting element facilitates minus-strand DNA synthesis during HBV RT
Herpesvirus - Herpesvirus protease inhibited by dimer disruption
Herpesvirus - KSHV-encoded latency-associated NA inhibits lytic replication by targeting Rta
Herpesvirus - Kaposi sarcoma-associated herpesvirus GP K8.1 is dispensable for virus entry
Hodgkin Disease - Epidemiology of Hodgkin disease requires further study
Immunology - T-cell differentiation distinct in persistent human virus infection
Immunotherapy - Cripto is novel target for antibody-based cancer immunotherapy
Influenza A Virus - PB1-F2 creates variably sized pores in planar lipid membranes
Knee Replacement - Timing of tourniquet release does not affect blood loss
Lead Poisoning - Follow-up shows blood lead levels decreased in children in Jamaica
Leukemia - HLA-A2 class I monomers may be used against leukemia-associated protein
Leukemia - New research has implications for mechanisms of VDJ recombination
Leukemia - Newly discovered property of leukemia cells may lead to novel treatment
Leukemia - PR CpG island aberrant hypermethylation may be genetic alteration in leukemia
Liver Failure - Positive preclinical data reported on blood purification device
Lung Cancer - Current smoking decreases survival of NSCLC patients following radiation therapy
Lung Transplantation - ABO-incompatible lung transplants may be feasible
Medical Communication - Peer-reviewed stem cell journal launched online and in print
Mergers & Acquisitions - Private umbilical cord blood stem cell banks merge
Metastasis - Anticoagulants interrupt metastatic events in solid tumors
Monoclonal Antibody - Novel mAb identifies and enriches quiescent satellite cells from adult muscle
Multipotent Cell Transplantation - Dermal multipotent cell transplant promotes recovery after sublethal irradiation
Nasopharyngeal carcinoma - Id1 induction by LMP1 may promote nasopharyngeal carcinoma of EBV-infected cells
Oncogenesis - Akt stimulates aerobic glycolysis in cancer cells
Oncogenesis - p53 mutants induce oncogenesis by transactivating growth-promoting genes
Personnel - Developer of artificial hearts names Sam Williams chief financial officer
Pharmaceutical & Drug Development - Lymphocytes transformed by EBV-related HSV may be useful for antiviral screening
Pharmaceutical & Drug Development - Powerdental helps prevent and treat oral and inflammatory diseases
Pharmaceutical & Drug Development - Protease inhibitor nelfinavir inhibits replication of coronavirus
Prognostic Indicator - Indicators predict survival/death in pediatric HSCT patients admitted to the ICU
Prostate Cancer - Zoledronic acid prevents SREs in hormone-refractory prostate cancer
Protein Equalization - Protein Equalizer beads launched
Protein Signal - SHP-1 and PMCA provide mechanism by which CD22 can affect calcium responses
Radiation Exposure - Diltiazem prevents gamma radiation-induced anemia
Renal Disease - Serum VEGF levels rise in patients with hemolytic uremic syndrome
Respiratory Virus - Human metapneumovirus contributes to upper and lower respiratory tract morbidity
Retrovirology - BAF has roles in chromatin, nuclear structure, and retrovirus integration
Retrovirus - Foamy virus reverse transcriptase has greater polymerase activity than HIV-1 RT
Schizophrenia - TP53 polymorphisms do not contribute to schizophrenia
Signet-Ring Cell Carcinoma - Immunohistochemical staining distinguishes SRCC of stomach/breast/colon
Stem Cell Research - Apoptosis increased in differentiating p27-deficient embryonic stem cells
Stem Cell Research - BM mesenchymal stem cells express glial markers and stimulate nerve regeneration
Stem Cell Research - Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme
Stem Cell Research - Dopaminergic neurons generated from embryonic SC isolated and transplanted
Stem Cell Research - Glial progenitors in CNS respond after injury and participate in repair
Stem Cell Research - Matrix metalloproteinase-9 produced by CD34+ stem cells from cord blood
Stem Cell Research - Neuronal differentiation of embryonic neural stem cells functionally deficient
Stem Cell Research - Plzf is required to regulate self-renewal and maintenance of stem cell pool
Stem Cell Research - Plzf required in adult male germ cells for stem cell self-renewal
Stem Cell Research - Raman microspectoscopy monitors mRNA translation in ESC during differentiation
Stem Cell Research - Retrovirus-mediated transduction selects for virus-specific T cells
Stem Cell Research - Small peptide analogs to SDF-1 enhance chemotactic migration of stem cells
Stem Cell Research - Tissue-specific expression of BAC transgene targeted to Hprt locus in ESCs
Stem Cell Research - c-Myc has direct role in stem cell fate determination
Stem Cell Transplantation - TNFA polymorphisms have functional effect on myeloid engraftment in HSCT
Tissue Engineering - Engineering gel structural changes facilitate cartilaginous tissue production
Tissue Engineering - Novel 3-D composite scaffold developed for large bone defect repair
Tobacco Use - Method to measure exhaled carbon monoxide levels assesses smoking status
Transfection - Viral and human elements combine to heighten transgene expression in B cells
Transfusion Medicine - Blood shortage reaches critical levels
Transplant Medicine - Transplantation tolerance induced by HY peptide intranasal administration
Tumor Detection - MRI detects lung tumors using partial liquid ventilation with PFC/water emulsion
Tumor Suppression - Mus81 expression has critical role in genome integrity and tumor suppression
Tumor Suppression - alpha-Tocopheryl succinate selectively suppresses proliferation of cancer cells
Viral Inhibition - Reovirus inhibition by mycophenolic acid associated with M1 genome segment
Virology - Detection of identical JC virus DNA sequences in both kidneys
Virus Infection - Chronic excretion of norovirus detected in child with cartilage hair hypoplasia
Wound Care - Flies offer clues to how wounds heal
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