Blood Weekly

Blood Donation - American Red Cross renews blood donation technology agreement with Haemonetics

Blood Products - Naturlose to be studied to extend blood shelf life

Blood Substitute - First interim analysis of polyheme ambulance study data announced

Hepatitis Epidemiology - HBV and HCV seromarker prevalence among blood donors in Saudi Arabia reported

Stem Cell Research - bHLH gene over-expression facilitates neural formation of embryonic stem cells

Allergy & Immunology - IL-1 receptor antagonist attenuates airway hyperresponsiveness to ozone

Allergy & Immunology - Interaction between parasitoses and allergy in third world countries elucidated

Allergy & Immunology - Short-term smoke exposure attenuates ovalbumin-induced airway inflammation

Angiogenesis - Bone marrow endothelial cells studied in ongoing angiogenesis

Angiology - Estrogen receptor associated with epithelioid variants of renal angiomyolipoma

Anti-Infectives - Pediatric patients require higher dosages of i.v. voriconazole than adults

Antimicrobials - Response surface approach able to interpret antifungal interactions

Antiretroviral Drug Resistance - Long-term suppression of HIV RNA with HAART occur despite virus evolution

Antiretroviral Therapy -  Clusiaceae species extracts inhibit HIV-1 reverse transcriptase

Antiretroviral Therapy - Addition of tenofovir decreases AUC for atazanavir in HIV-treated patients

Antiretroviral Therapy - Atazanavir suppresses HIV with extended use and in nelfinavir-switched patients

Antiretroviral Therapy - Microglia-expressed MRPs may restrict permeation of antiretroviral drugs

Antiretroviral Therapy - Mutation D30N not selected by HIV-1 subtype C in nelfinavir resistance

Antiretroviral Therapy - Novel S-DABO derivatives inhibit HIV-1 and HIV-2

Antiretroviral Therapy - Novel fungal polyketide inhibits HIV-1 integrase activity

Antiretroviral Therapy - Novel thia-DCK analogues inhibit HIV replication in vitro

Antiretroviral Therapy - Previous immunosuppression predicts incomplete immune reconstitution after HAART

Antiretroviral Therapy - Ribinucleotide reductases attenuate efficacy of abacavir

Antiretroviral Therapy - Sustained HIV virological response better with triple nucleoside therapy

Aplastic Anemia - T-cell repertoire returns to normal in HAA recovery

Aspergillosis - ABLC best therapeutic choice to decrease systemic Aspergillus fumigatus burden

Bacterial Resistance - Infection control measures should guide methicillin-resistant S. aureus control

Bacteriology - Clip-and-link activity of repeat in gram-negative pathogen RTX proteins found

Bacteriology - Homologue of aliB found in capsule region of nonencapsulated S. pneumoniae

Biological Markers - DC-SIGN is a marker for dendritic cells and alternatively activated macrophages

Blood Supply - Urgent blood donation appeal issued to NY/NJ metropolitan community

Breast Cancer - Steroid sulfatase inhibitors inhibit MCF-7 breast cancer cell gene activation

Cancer Markers - H3 mRNA level new proliferative marker in astrocytomas

Cancer Metastasis - hsp90 alpha has essential extracellular role in cancer cell invasiveness

Cardiac Surgery - Recombinant activated factor VII may have a role in cardiac surgery

Cardiology - Acute graft attrition after myoblast transplantation to the heart studied

Chemokine Receptor - Low pH not required for RANTES or MIP-1beta dissociation from CCR5

Complementary & Alternative Medicine - Cadalene extract exerts antioxidative effect on NNK-induced lung tumorigenesis

Complementary & Alternative Medicine - Ocimum extract and its flavonoids do not protect solid tumors

Cord Blood Transplant - Biotech company provides stem cell technology as public service

Coronary Bypass Surgery - Blood transfusions during heart surgery may increase death risk

Coronavirus - Novel peptides inhibit SARS coronavirus

Coronavirus - SARS-associated coronavirus infection inhibited by immoral immune response

DNA Microarrays - DNA microarrays used as a tool in toxicogenomics

DNA Repair - FANCD2 has direct interaction with BRCA2 in DNA damage response pathways

Diagnostics - One-step quantitative RT-PCR assay detects SARS coronavirus

Drug Delivery - New generation of polymer nanoparticles for drug delivery developed

Embroyonic Research - Deletion of P450c17 gene causes early embryonic lethality

Finance - Fluvirin maker reports Q2 earnings down due in part to PowderJect acquisition

Gene Expression - Hepatocyte nuclear factor-1beta-regulated genes identified

Gene Expression - WT1 gene expression studied as marker for minimal residual disease JMML and MDS

Gene Mutation - One-allele inactivation of AML1 has role in development of overt disease

Gene Therapy - HSV immortalized T cells are gene therapy model for primary immunodeficiencies

HIV/AIDS - Persistent apoptosis in HIV patients associated with poor recovery of CD4 cells

HIV/AIDS Healthcare - Knowledge gap increases HIV contagion fear in nurses in Uganda

HIV/AIDS Research - AA substitutions in multidrug-resistant HIV RT leads to drug resensitization

HIV/AIDS Research - HIV fitness loss correlates with poor ability of K65R/L74V RT to use nucleotides

HIV/AIDS Research - Insertion of CD80 (B7.1) and CD86 (B7.2) into HIV-1 affects virus life cycle

HIV/AIDS Research - New generation of SNV-based vectors may be used to block HIV-1 replication

HIV/AIDS Research - theta-Defensin composed exclusively of D-amino acids active against HIV-1

HIV/AIDS Screening - Use of two HIV antibody screening tests increase false-positive rate

HIV/AIDS Therapy - Immune recovery slows after 3 years HAART and reaches plateau after 4-5 years

HIV/AIDS Transmission - Acceptance of HAART intervention independent of maternal immune status

HIV/AIDS-Associated Lipodystrophy - Rosiglitazone induces gene expression in adipose tissue in HAL patients

HIV/AIDS-Related Disease -  Pneumocystis activates AM NF-KB signaling through mannose receptors

HIV/AIDS-Related Encephalitis - IL-16 expressed in lymphocytes and microglia in HIV-1 encephalitis

HIV/AIDS-Related Lipodystrophy - HIV-related lipodystrophy caused by multiple factors

Healthcare & Politics - Stem cell journal papers available free online through November 2, 2004

Heart Disease Therapy - Combination anticlotting therapy increases risk of bleeding