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Sepsis

Sepsis-associated gene expression profiles identified

Published in Blood Weekly, August 19th, 2004

Sepsis-associated gene expression profiles have been identified, providing information that could be valuable in diagnosis.

"Sepsis is a common and serious health problem whereby improvements in diagnosis are crucial in increasing survival rates," scientists in Germany explained.

"To test whether profiling transcription is applicable to sepsis diagnosis," M. Prucha and colleagues at the SIRS Laboratory in Jena "analyzed whole blood using a microarray containing probes for 340 genes relevant to inflammation."

"The patient's gene expression pattern was highly homogenous, resulting in 69% of differentially expressed genes," published...

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