Stem Cell Research

HAPO acts on primitive cells of hematopoietic and endothelial cell lineages

Published in Blood Weekly, August 26th, 2004

A novel growth factor acts on the primitive cells of hematopoietic and endothelial cell lineages.

"The cells of hematopoietic and vascular endothelial cell lineages are believed to share a common precursor, termed hemangioblast. However, the existence of a growth factor acting relatively specifically on hemangioblasts remains unclear.

"Here we report the identification of hemangiopoietin (HAPO), a novel growth factor acting on both hematopoietic and endothelial cell lineages," scientists in China report.

"In vitro in the human system," said Y.J. Liu and coworkers, "recombinant human HAPO (rhHAPO) significantly stimulated the...

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Source: Blood Weekly (2004-08-26)

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