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Trypanosomiasis

Genetic stability seen in natural clones of Trypanosoma brucei

Published in Blood Weekly, August 26th, 2004

Genetic stability was seen in natural clones of Trypanosoma brucei.

"In order to improve our knowledge about the taxonomic status and the population structure of the causative agent of human African Trypanosomiasis in the Central African subregion, 169 newly isolated stocks, of which 16 came from pigs, and 5 reference stocks, were characterized by multilocus enzyme electrophoresis, for 17 genetic loci," investigators in Cameroon report.

"We identified 22 different isoenzyme profiles or zymodemes, many of which showed limited differences between them. These zymodemes were equated to multilocus genotypes," F. Njiokou and coworkers wrote.

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