HIV/AIDS Research
Brownian adhesive dynamics (BRAD) simulate receptor-mediated binding of viruses
Published in Blood Weekly, September 2nd, 2004
According to a study from the United States, "Current viral docking models have relied upon the assumption that bond formation and breakage are independent of viral and docking surface geometry, as well as the forces exerted on the bonds.
"This assumption, known as the equivalent site hypothesis (ESH), is examined in detail using a newly developed simulation technique-Brownian adhesive dynamics (BRAD)."
"The simulation couples the thermal motion of viral particles with adhesive dynamics models to characterize the effect of bonding on viral motion. We...
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Source: Blood Weekly (2004-09-02)
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