Hematology

Erythropoietin is a potent booster of metallothionein gene expression

Published in Blood Weekly, September 2nd, 2004

Erythropoietin is a potent booster of metallothionein gene expression.

According to recent research published in the journal Experimental Biology and Medicine, "recent evidence has demonstrated an appreciable expression of metallothionein (MT) in erythrocytes. However, the induction of the MT protein by hematopoietic growth factors and its subsequent functional significance on clonal expansion or differentiation of erythroid progenitor cells remain elusive. We therefore examined the effects of growth factors erythropoietin (EPO), granulocyte-monocyte colony-stimulating factor (GMCSF), and interleukin-3 (IL-3) on MT gene expression in erythroid progenitor K562...

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Source: Blood Weekly (2004-09-02)

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