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Stem Cell Transplantation

Hepatocytes obtained after graft reduction may be used for liver transplant

Published in Blood Weekly, September 9th, 2004

Hepatocytes obtained after graft reduction may be used for liver transplantation.

"This article describes results obtained when human liver cells obtained from reduced grafts are cultured in a chemically defined medium," scientists in Argentina report.

"Remnants of livers after reduction for pediatric transplantation were processed by a multiple cannulation system through the existing vasculature, which allowed the homogeneous perfusion of collagenase. The graft weight ranged between 55 and 1000 g (median value: 145.6 g).

"The yield ranged between 0.13x106 and 38x106 cells/g of tissue (median value...

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