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Antiretroviral Therapy



Novel drug approaches minimize development of HIV-1 resistance to NNRTIs



September 9th, 2004

Novel drug approaches minimize the development of HIV-1 resistance to non-nucleoside reverse transcriptase inhibitors.

According to recent research published in the International Journal of Biochemistry and Cell Biology, "Non-nucleoside reverse transcriptase inhibitors are potent, highly specific, noncompetitive inhibitors of the Human immunodeficiency virus type I (HIV-1) reverse transcriptase.

"They are used commonly as part of potent antiretroviral regimens for the treatment of HIV-1 infection, either in combination with nucleoside analogs, protease inhibitors, or both."

"A major limitation to the success of...


Source: Blood Weekly (2004-09-09)

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