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Blood Weekly

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Bacterial Genomics



 S. dysenteriae 1 isolates derived from clone from single phage-integration event



September 9th, 2004

Shigella dysenteriae 1 isolates are derived from a clone resulting from a single phage-integration event.

"The Shiga toxin (Stx) region of Shigella dysenteriae 1 lies on a defective prophage homologous to lambdoid bacteriophages in Stx-producing Escherichia coli.

"S. dysenteriae 1 strains obtained in locations throughout the world over the course of the past 60 years were assessed for variations in the Stx region by use of polymerase chain reaction and sequence analysis," scientists in the United States report.

"The defective prophage was present in all strains examined," wrote K.M. Greco and coworkers,...


Source: Blood Weekly (2004-09-09)

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