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Bioengineering
Delta LNGFR is a viable gene marker in engineered tissues
September 9th, 2004
Delta LNGFR is a viable gene marker in engineered tissues. According to a study from the Netherlands, "the use of bone marrow derived stromal cells (BMSC's) for bone tissue engineering has gained much attention as an alternative for autologous bone grafting. Little is known however, about the survival and differentiation of the cells, especially in the clinical application. The aim of this study was to develop a method to trace goat BMSC's in vivo." "We investigated retroviral genetic marking, which allows stable expression of the label with cell division. Goat BMSC's were subjected to an amphotropic envelope containing a MoMuLV-based vector...
Source: Blood Weekly (2004-09-09)
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