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Breast Cancer
EGR3 involved in estrogen-signaling pathway in breast cancer
September 9th, 2004
EGR3 is involved in the estrogen-signaling pathway in breast cancer. According to recent research from Japan, "Estrogen has been closely associated with the genesis and malignant progression of breast cancer. However, the molecular mechanism underlying the effects of estrogen is far from being completely clarified." "We previously developed a custom-made cDNA microarray consisting of approximately 200 estrogen-responsive genes in breast cancer cells. Using this system," A. Inoue and coworkers reported, "we found one estrogen-induced gene in various cancer cell lines, including breast cancer MCF-7 cells, which encode a zinc-finger transcription...
Source: Blood Weekly (2004-09-09)
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