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Cytomegalovirus
CMV viral proteins have adapted by functionally mimicking cellular genes
September 9th, 2004
Cytomegalovirus viral proteins have adapted by functionally mimicking cellular genes. According to a study from France, "The human cytomegalovirus (HCMV) genome has evolved with its host by incorporating a series of genes that are homologous to, or functionally mimic, cellular genes. "Some are designed to counteract the stress of infection on the host cell, notably the viral antiapoptotic proteins (vICA, vMIA). Others potentially help the infected cell maintain a low immunologic profile." "These include virus-encoded chemokine receptors (UL33, UL78, US27, US28), FcRs (gp TRL11/IRL11, gp UL119-118), and proteins that directly or...
Source: Blood Weekly (2004-09-09)
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