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Cytomegalovirus
Formation of effector memory CD4+ cells necessary for recovery of CMV infection
September 9th, 2004
Formation of effector memory CD4+ cells is necessary for the recovery of cytomegalovirus infection. According to recent research published in the journal Human Immunology, "The correlates of protective immunity to disease-inducing viruses in man remain to be elucidated. We determined the kinetics and properties of cytomegalovirus (CMV)-specific CD4+ T cells in healthy individuals and renal transplant recipients during different stages of CMV infection." "Our data reveal that circulating CMV-specific CD4+ T cells displayed an effector-memory phenotype, and produced the T helper 1 cytokines interferon-gamma and tumor necrosis...
Source: Blood Weekly (2004-09-09)
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