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Cytomegalovirus
Late CMV infection associated with SCT history of early CMV infection
September 9th, 2004
Late CMV infection is associated with donor lymphocyte infusion history of early CMV infection. "An increased incidence of late cytomegalovirus (CMV) infection has been reported during the last decade since the introduction of ganciclovir (GCV) prophylaxis or GCV pre-emptive therapy. Given that a donor lymphocyte infusion (DLI) can induce more severe GVHD, this may predispose a patient to late CMV infection," scientists in South Korea report. "In all, 64 patients (median age 36, M/F 38/26) underwent allogeneic stem cell transplantation (SCT) using a matched sibling donor with bone marrow (n=9) or peripheral blood stem cells (n=55). The overall...
Source: Blood Weekly (2004-09-09)
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