Blood Weekly
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Blood Weekly
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Diagnostics
False-negative syphilis test occurs in HIV infection due to prozone phenomenon
September 9th, 2004
False-negative syphilis tests may occurs in HIV infection due to the prozone phenomenon. "The prozone phenomenon in syphilis testing refers to a false negative response resulting from overwhelming antibody titers which interfere with the proper formation of the antigen-antibody lattice network necessary to visualize a positive flocculation test," wrote investigators in the Southern Medical Journal. "This prozone effect in syphilis testing can be expected in cases of disproportionately high antibody titers, such as secondary syphilis, or with human immunodeficiency virus (HIV) coinfection," G. Smith and coauthors wrote. ...
Source: Blood Weekly (2004-09-09)
|
