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HIV/AIDS Diagnostics
Immuno-PCR for HIV-1 p24 antigen lowers HIV-1 viral load detection limits
September 9th, 2004
According to recent research published in the American Journal of Clinical Pathology, "Presently, the assay that attains maximal sensitivity and dynamic range of HIV-1 viral copy number (50 copies per milliliter) is nucleic acid amplification of HIV RNA in plasma. "Enzyme-linked immunosorbent assay (ELISA) methods for quantification of HIV-1 p24 antigen have been relatively insensitive. In this report, we show data that indicate real-time immuno polymerase chain reaction (IPCR), a combination of the ELISA and PCR techniques, is more sensitive for HIV-1 p24 antigen detection than other currently reported methods." "When derived from an IPCR...
Source: Blood Weekly (2004-09-09)
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