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AIDS/HIV Therapy
Systematic HAART for HIV patients with >500 T cell counts not supported by data
September 9th, 2004
The data does not support systematic highly active antiretroviral therapy for HIV patients with >500 T cell counts. "To assess the clinical, immunological and virological evolution in HIV-1 infected patients with CD4 T-cell count above 500/mm3, a historical cohort of 202 untreated and 96 patients treated with HAART was longitudinally studied (median follow up 36 months)," wrote investigators in France. "Fourteen untreated and 2 treated patients experienced clinical progression (p=.09). The difference between baseline CD4 T-cell count and after 3 years was -240/mm3 in the untreated group vs. +19/mm3 in the HAART...
Source: Blood Weekly (2004-09-09)
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