AIDS/HIV Therapy

Systematic HAART for HIV patients with >500 T cell counts not supported by data

Published in Blood Weekly, September 9th, 2004

The data does not support systematic highly active antiretroviral therapy for HIV patients with >500 T cell counts.

"To assess the clinical, immunological and virological evolution in HIV-1 infected patients with CD4 T-cell count above 500/mm³, a historical cohort of 202 untreated and 96 patients treated with HAART was longitudinally studied (median follow up 36 months)," wrote investigators in France.

"Fourteen untreated and 2 treated patients experienced clinical progression (p=.09). The difference between baseline CD4 T-cell count and after 3 years was -240/mm³ in the untreated group vs. +19/mm³ in the HAART...

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Source: Blood Weekly (2004-09-09)

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