Susan Hasty, Publisher
Table of Contents . . . September 23rd, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Blood Weekly | Other Publications
Bacterial Detection - Novel assay improves detection rate of diarrhea-causing bacteria in stool
Blood Safety - U.S. Dept. of Defense funds Mirasol Pathogen Reduction Technology development
Blood Substitute - Blood substitute developer receives funding from Defense Appropriations Bill
Diagnostics - Serum procalcitonin more accurate than CRP as marker of bacterial infection
Stem Cell Transplantation - Neural stem cell transplants improve motor function in Huntington disease
Acute Myeloid Leukemia - Many questions about AML remain unanswered, and controversy continues
Angiology - Promising new anticoagulant offers fibrin-targeted factor Xa inhibition
Antiretroviral Therapy - HAART improves course of hepatitis C virus infection in HIV coinfected patients
Antiretroviral Therapy - Novel bioelectronic method detects HIV-1 drug resistance
Aspergillosis - Invasive aspergillosis before HSCT decreases patient survival
Aspergillus Terreus - Voriconazole may be better than a polyene for Aspergillus terreus infection
Bacterial Infection - Age/primary infection foci differs in invasive/noninvasive group A streptococci
Blood Banking - Lyophilization more successful with mononuclear cells than whole-cord blood
Blood Volume Analysis - Ohio independent diagnostic imaging center contracts for BVA-100
Breast Cancer - Estradiol-linked genotoxicants kill estrogen receptor-expressing cancer cells
Breast Cancer - Five or more circulating tumor cells may indicate more aggressive breast cancer
Breast Cancer - Liposome delivery of monesin overcomes problem of drug resistance
Cardiac Ischemia - Benidipine attenuates postischemic myocardial apoptosis
Cholera - Chironomid egg masses natural reservoir of V. cholerae non-O1 and non-O139
Chronic Hepatitis B - HBV-positive kidneys merit prudent use in HBV-infected transplant recipients
Chronic Hepatitis C - Interferon-alpha is a safe therapy for liver transplant patients
Clinical Trials - Phase 2a trials reopened as U.S. FDA, pharmaceutical company reach agreement
Collaborations - Biophysics company, Walter Reed agree to research biting insect problems
Collaborations - Blood center partners with UW to expand cord blood program
Collaborations - CuraGen inks collaboration with the NCI for clinical development of PXD101
Colorectal Cancer - qRT-PCR assay for CEA mRNA identifies disseminated tumor cells
Complementary & Alternative Medicine - Cannabinoids effective against cachexia-anorexia syndrome in HIV patients
Coronavirus - Structural basis proposed for coronavirus-mediated membrane fusion
Correctional Health - Organized healthcare delivery in Texas prison system improves health outcomes
Cryptosporidiosis - Cryptosporidiosis outbreak associated with a recreational swimming pool
Cytomegalovirus - Necrotizing enterocolitis with atypical features may signal infant CMV infection
Diagnostics - Nested PCR more sensitive than real-time PCR for detection of T. gondii
Diagnostics - Real-time PCR sensitive/specific for P. jiroveci from bronchoalveolar lavage
Endocrinology & Metabolism - Aerobic fitness associated with increased recovery of exercise-related hormones
Epidemiology - Infectious disease early-warning monitoring program free to Internet users
Epidemiology - Novel epidemic model presents a two-phase epidemic driven by diffusion
Escherichia Coli - Pathogenic E. coli in soil/vegetables contaminated with manure composts
Fungal Infection - Candida dubliniensis isolated from non-HIV-infected patients in Kuwait
Fungal Therapy - P. jiroveci DHPS polymorphisms confer resistance to sulfa drugs
Fungal Therapy - Fluconazole prophylaxis does not affect cortisol levels in critical illness
Fungal Therapy - Posaconazole is a new and potent antifungal medication
Genomics - Small interfering RNAs silence disease-related genes
HIV Coinfection - HIV-HTLV-I/II coinfection increases risk of clinical complications
HIV/AIDS Coinfection - S. mansoni and HIV-coinfected patients mount specific immune response
HIV/AIDS Coinfection - Cytomegalovirus coinfection could affect HIV-1 disease progression in women
HIV/AIDS Gene Therapy - Novel target site for gene therapy may control/manage HIV-1 infection
HIV/AIDS Research - CpyA retrotransposition into TRIM5 explains owl monkey resistance to HIV-1
HIV/AIDS Research - HIV hollow-fiber SCID model more cost effective than SCID/hu to evaluate therapy
HIV/AIDS Research - HIV replication rates should vary between cells with different lifespans
HIV/AIDS Research - HIV-1 -->Vpr sequence translocates bioactive macromolecules directly into nucleus
HIV/AIDS Research - Insect antiviral compound effective against HIV-1
HIV/AIDS Research - Novel approach analyzes immune response of HIV-infected individuals
HIV/AIDS Research - Novel component of innate immune system lethally hypermutates retroviruses
HIV/AIDS Research - Opiates enhance HIV-1 Tat cytotoxicity by direct actions on glial precursors
HIV/AIDS Research - Poly(acrylic acid) inhibits HIV-1 TAR RNA-Tat peptide interaction
HIV/AIDS Research - Progenitor cells may be a reservoir for HIV-1 in the brains of infected patients
HIV/AIDS Research - Replication-competent HIV-2 found in patients with undetectable viremia
HIV/AIDS Therapy - ART initiation during early infection results in lower residual HIV reservoirs
HIV/AIDS Therapy - Company reports preliminary data from Study 934, of HIV therapies
HIV/AIDS Therapy - Enfuvirtide long-term HIV therapy has few side effects
HIV/AIDS Therapy - HIV protease inhibitors directly interfere with insulin secretion
HIV/AIDS Therapy - Initiation of HAART being rethought amid toxicity/adherence concerns
HIV/AIDS Therapy - Lifetime control of HIV infection with HAART may be possible
HIV/AIDS Therapy - Mycophenolate mofetil and HAART delays viral load rebound in HIV infection
HIV/AIDS Therapy - Perirenal fat diameter early predictor of HAART-associated lipodystrophy
HIV/AIDS Therapy - Population model projects effect of HAART on evolution of HIV life history
HIV/AIDS Therapy - Social support/positive state of mind increases HIV treatment adherence
HIV/AIDS Treatment - Retinol assessment in HIV infection evaluates vitamin A deficiency in former IDU
HIV/AIDS-Associated Infection - ADA in CSF limited utility for tuberculous meningitis diagnosis in HIV infection
Hantavirus - Human and environmental factors caused hantavirus pulmonary syndrome outbreak
Heart Transplantation - Eighth implant of the VentrAssist "artificial heart" announced
Hematology - Factor VIII is retained in cellular intermediates during secretion
Hemorrhagic Fever - Ribavarin therapy effective against Crimean-Congo hemorrhagic fever
Hepatitis B Virus - Clevudine potent and tolerable in hepatitis B virus-infected patients
Hepatitis C Virus - Glycoprotein E2 has mechanistic features in common with class II fusion proteins
Hepatitis C Virus - HCV coinfection associated with higher risk of diabetes in HAART era
Hepatitis C Virus - Hepatitis C virus infection associated with increased risk of malignant lymphoma
Hepatitis C Virus - Peginterferon and ribavirin safe/effective in HCV-infected methadone patients
Immunology - Cytokine mutations associate with recurrent HCV after liver transplantation
Immunology - Novel method allows for selective adsorption of CD4+ T cells
Infectious Disease - Children at greatest risk of infection by enteric pathogens
Lung Transplantation - Pharma company granted Orphan Medicial designation for inhaled cyclosporine
Lymphoma - Analysis of gene expression in lymphoid cells can determine cancer
Lypodystrophy - PI substitution with abacavir in severe lipodystrophy markedly reduces lipolysis
Male Infertility - Teratocarcinoma-derived germ cells used to elucidate male infertility
Medical Devices - BioArchive system chosen for the new M.D. Anderson Cord Blood Stem Cell Bank
Medical Devices - Instruments company establishes award for advancements in organ preservation
Mergers & Acquisitions - Chiron acquires vCJD-focused company
Microbicides - HIV topical microbicides entering clinical trials should be reevaluated
Microbicides - PSC-RANTES blocks R5 HIV infection in immature Langerhans cells
Multiple Myeloma - Myeloma Institute at UAMS receives nearly $18 million grant from NCI
Myocardial Infarction - The optimal time to rebuild myocardium from BMDPC is within 2 weeks of MI
Obstetrics - Parvovirus B19 infection can cause dyserythropoietic anemia in pre-eclampsia
Oncogenesis - Hepatitis C virus infection may cause intrahepatic cholangiocarcinoma
Pain Medicine - Cannabinoids do not induce serious/relevant immunosuppression in humans
Parasitiology - G. lamblia encystation dependent on novel transglutaminase activity
Patents - Cord-blood company licenses its patents to 80% of private cord-blood companies
Personnel - Dennis F. Marr named vice president of R&D for blood bank equipment company
Personnel - Drug development company names VP clinical development to lead Viprinex team
Personnel - Stem cell company retains Dr. Avraham Treves to consult on development efforts
Platelet Donation - Kansas couple plans trip to donate platelets at 35 blood donation centers
Pseudomonas - Transmissible P. aeruginosa in cystic fibrosis identified/characterized
SARS - Infectious disease consultants in U.S. question hospital preparedness for SARS
Salmonella - PCR primer pair based on 16S rDNA detects Salmonella serovars in food samples
Stem Cell Research - 17 Beta-estradiol enhances neuronal differentiation of embryonic stem cells
Stem Cell Research - 5-Azacytidine induces stem cells to differentiate into cardiomyocyte phenotype
Stem Cell Research - ABC transporter inhibitors enhance hematopoietic progenitor cell transduction
Stem Cell Research - Critical temporal requirement for RB genes during neuronal MSC differentiation
Stem Cell Research - Cryopreserved cord blood fractions alternative source of mesenchymal stem cells
Stem Cell Research - Dose rate at which lethal dose of TBR is delivered does not augment SC homing
Stem Cell Research - FgFr1 required for the proliferation of hippocampal progenitor cells
Stem Cell Research - Genes induced by GDNF overproduction of neuronal progenitor cells characterized
Stem Cell Research - Human cells for research and testing need to overcome longevity/culture problems
Stem Cell Research - Known and novel transcripts overexpressed in hematopoietic stem cells identified
Stem Cell Research - Neural stem cells in the subventricular zone resilient to hypoxia/ischemia
Stem Cell Research - Over 1700 human embryonic stem cell-material interactions characterized
Stem Cell Research - Public confused about role of adult stem cells, new NeoStem survey shows
Stem Cell Research - Serum-free media improve generation of embryonic stem cells
Stem Cell Research - Strategy proposed for breast stem cells to ignore mitogenic effects of estrogen
Stem Cell Transplantation - Allogeneic stem cell transplantation is safe in elderly patients
Syphilis - Increased syphilis testing coincided with public health interventions
Testicular Cancer - CIS/ITGCNU arises from developmentally arrested germ cells
Transplant Medicine - Cyclosporine A and PI interactions in liver transplantation can be managed
Transplant Medicine - Interleukin-4 gene transfer delays acute splenic allograft rejection in rats
Transplant Medicine - NOS isoforms have distinctive role during reperfusion following ischemia
Transplant Medicine - Obesity increases morbidity in kidney transplantation
Transplant Medicine - Pre-emptive antivirals aid living donor liver transplant recipients
Transplantation Medicine - Study finds heart transplant device reduces mortality in critically ill patients
Tuberculosis - Financial difficulties influence TB care-seeking behavior in rural China
Valve Prostheses - Study analyzes the closing behavior of mechanical aortic heart valve prostheses
Viral Evolution - Cross-reactive immunity leads to viral evolution, which limits extent of disease
West Nile Virus - Donated blood tests positive for West Nile virus
Wiskott-Aldrich Syndrome - Probing the surface of white blood cells enhances immune system medicine
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