Fungal Therapy
Fluconazole prophylaxis does not affect cortisol levels in critical illness
Published in Blood Weekly, September 23rd, 2004
According to a study from the United States, "Fluconazole is widely used in the intensive care unit for prevention and treatment of fungal infections. Case reports have described an association between fluconazole and adrenal dysfunction, an important cause of morbidity and mortality in critically ill patients.
"We sought to determine whether 400 mg of fluconazole per day administered to critically ill surgical patients was associated with a reduction in cortisol levels."
"Cortisol levels were measured in stored plasma specimens drawn from 154...
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Source: Blood Weekly (2004-09-23)
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