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Serum procalcitonin more accurate than CRP as marker of bacterial infection

Published in Blood Weekly, September 23rd, 2004

Serum procalcitonin is more accurate than C-reactive protein as a marker of bacterial infection.

"A meta-analysis was performed to evaluate the accuracy of determination of procalcitonin (PCT) and C-reactive protein (CRP) levels for the diagnosis of bacterial infection. The analysis included published studies that evaluated these markers for the diagnosis of bacterial infections in hospitalized patients," scientists in the United States report.

"PCT level was more sensitive (88% [95% confidence interval {CI}, 80%-93%] vs. 75% [95% CI, 62%-84%]) and more specific (81% [95% CI, 67%-90%] vs. 67% [95% CI, 56%-77%]) than CRP level for differentiating...

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