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HIV/AIDS Therapy

Lifetime control of HIV infection with HAART may be possible

Published in Blood Weekly, September 23rd, 2004

Lifetime control of HIV infection with highly active antiretroviral therapy may be possible.

According to published research from the United States, "Despite the remarkable success of highly active antiretroviral therapy (HAART) for the treatment of HIV-1 infection, it now appears that the infection is intrinsically incurable with antiretroviral therapy alone.

"The major reason is that the virus can persist in a latent form in resting memory CD4 cells. These cells arise when infected CD4+ lymphoblasts carrying an integrated copy of the HIV-1 genome revert back to a resting memory state."

"In this resting state, CD4 cells are...

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