Herpesvirus

HSV-2 EIAs vary in sensitivity/specificity of sub-Saharan African samples

Published in Blood Weekly, September 30th, 2004

Herpesvirus type 2 enzyme immunoassays vary in sensitivity/specificity when tested against specimens from sub-Saharan Africa.

According to a study from Belgium, "Data are accumulating on the performance of enzyme immunoassays (EIAs) for the detection of herpes simplex virus type 2 (HSV-2) infection in North America and Europe, but little is known about their performance in other populations."

"Nine test kits were evaluated with 330 serum samples from sub-Saharan Africa. The tests were first compared to the monoclonal antibody (MAII) EIA (Central Public Health Laboratory, London, United Kingdom).

"Samples that gave discordant...

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Source: Blood Weekly (2004-09-30)

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