Stem Cell Research

Bone marrow stromal cells alternative source for SCT in liver repair

Published in Blood Weekly, September 30th, 2004

Bone marrow stromal cells are an alternative source for stem cell transplantation in liver repair.

According to a study from China, "Bone marrow comprises heterogeneous cell populations, of which certain progenitors have demonstrated the ability to differentiate into multiple mesenchymal cell lineages.

"This study demonstrates the bone marrow stromal cells (BMSCs) with intrinsic plasticity to differentiate into hepatocyte-like phenotypes under in vitro induction of hepatocyte growth factor (HGF)."

"BMSCs isolated from rat femurs and tibias were cultured and passaged 3-4 times in the presence of HGF. Cells were harvested on days 0,...

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Source: Blood Weekly (2004-09-30)

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