Herpesvirus
Post-transcriptional regulator of KSHV controls gene expression through IRES
Published in Blood Weekly, October 7th, 2004
According to recent research from Japan, "Kaposi's sarcoma-associated herpesvirus (KSHV; also known as human herpesvirus 8, HHV-8) belongs to the gamma-herpesvirus subfamily. The KSHV ORF57 gene is thought to be a homolog of posttranscriptional regulators that are conserved in the herpesvirus family and are essential for replication."
"We generated specific monoclonal antibodies (mAbs) against the ORF57 protein that detected the 51-kDa protein expressed in the nucleus of KSHV-infected cells.
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Source: Blood Weekly (2004-10-07)
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