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SARS Coronavirus

Intestinal cell line permissive to SARS coronavirus

Published in Blood Weekly, October 14th, 2004

An intestinal cell line is permissive to SARS coronavirus.

"Severe acute respiratory syndrome coronavirus (SARS-CoV) can produce gastrointestinal symptoms. The intestinal tract is the only extrapulmonary site where viable viruses have been detected. This study examined seven established human intestinal cell lines, DLD-1, HICT-116, HT-29, LoVo, LS-180, SW-480 and SW-620, for their permissiveness to SARS-CoV infection," researchers in China report."

"The results showed that only LoVo cells were permissive to SARS-CoV infection as evident by positive findings from indirect immunofluorescence staining for intracellular viral antigens, in situ...

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