Immunology

C5a receptor essential for optimal generation of antiviral CD8+ T cell response

Published in Blood Weekly, October 21st, 2004

The C5a receptor is essential for optimal generation of antiviral CD8+ T cell responses.

According to published research from the United States, "The complement system has been long regarded as an important effector of the innate immune response. Furthermore, complement contributes to various aspects of B and T cell immunity. Nevertheless, the role of complement in CD8+ T cell antiviral responses has yet to be fully delineated."

"We examined the CD8+ T cell response in influenza type A virus-infected mice treated with a peptide antagonist to C5aR to test the potential role of complement components in CD8+ T cell responses," wrote A.H.J. Kim and...

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Source: Blood Weekly (2004-10-21)

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