Published in Blood Weekly, October 21st, 2004
"Fibroblast growth factor I (FGF1, also known as acidic FGF) protects selective neuronal populations against neurotoxic effects such as those in Alzheimer's disease (AD) and HIV encephalitis. The FGF1 gene is therefore a strong candidate gene for AD," researchers in Japan report.
"Using the promoter polymorphism of the FGF1 gene," wrote H. Yamagata and coauthors, "we examined the relationship between AD and the FGF1 and apolipoprotein E (APOE) genes in 100 Japanese autopsy-confirmed late-onset AD patients and 106 age-matched non-demented controls."
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