Susan Hasty, Publisher
Table of Contents . . . October 28th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Blood Weekly | Other Publications
Cord Blood - Umbilical cord blood transplant after nonmyeloablative conditioning is promising
Hemophilia - Viruses bearing transgene generate coagulation factor in hemophilia A models
Liver Regeneration - Fluidized bed bioreactor has potential for extracorporeal liver supply
Non-Hodgkin Lymphoma - Allogeneic blood transfusion does not increase risk of non-Hodgkin lymphoma
Obstetrics - Diagnosis and management of twin-twin transfusion syndrome reviewed
Tissue Engineering - Novel scaffolds may be very useful for vascular tissue engineering
Acute Myelogenous Leukemia - Collaboration to develop immunostimulant, therapeutic vaccine approaches for AML
Adenovirus - Nosocomial infections in Japan caused by new adenovirus type 4 genomic variant
Allergy & Immunology - S. aureus protein A induces airway inflammatory response by TNFRI activation
Angiology - Blood platelet components are important elements of angiogenesis
Antimicrobial Susceptibility - Real-time PCR detects A. phagocytophilum susceptibility to antimicrobials
Apoptosis - P63 and p73 not required for development and p53-dependent apoptosis of T cells
Atrophic Gastritis - Genetics/lifestyle influence protective effect for developing atrophic gastritis
Bacterial Resistance - Salmonellae acquire antimicrobial resistance independent of selection pressure
Biowarfare - Defensive measures elucidated for agents of biological warfare
Blood Collection - Twice as many red blood cells collected in one session at Stanford blood center
Bovine Spongiform Encephalopathy - Italy detects another case of mad cow disease
Brain Cancer - Temozolomide well tolerated in patients with primary CNS lymphomas
Breast Cancer - Genomic testing identifies chromosomal changes in sporadic breast cancer
Cardiovascular Disease - Drug discovery company reports acute peripheral arterial occlusion trial
Cardiovascular Surgery - Hemostatic activity in different PCIs compared
Chemotherapy - Imatinib mesylate inhibits T-cell growth and delayed-type hypersensitivity
Chemotherapy - PEI regimen active/well tolerated for sensitive relapsed small-cell lung cancer
Clinical Trials - Results in phase 2 clinical trial of claudication arterial drug announced
Congestive Heart Failure - Stem cell therapy improves heart function after heart attacks
Cytochrome P450 - CYP450 genetic polymorphism screening can optimize cancer treatment
Cytomegalovirus - Phase 1 clinical trial for cytomegalovirus gene encoded vaccine initiated
DNA Repair - Cadmium inhibits DNA mismatch repair
Decontamination - Surface sampling/QPCR analysis effective for decontamination strategy evaluation
Dermatology - EphA4 and twist are aberrantly expressed in Sezary syndrome
Diabetes Complications - Platelet activation in type 2 diabetes reviewed
Diagnostics - Blood group typing and antibody device development approved by FDA
Diagnostics - Correlations between magnesium status of neonates and mothers from blood/hair
Diagnostics - Methods for detection of Enterocytozoon bienuesi in stool specimens compared
Diagnostics - Novel PCR assay useful for rapid detection of emetic Bacillus cereus
Diagnostics - Quantitative real-time PCR useful for diagnosis of ocular toxoplasmosis
Diagnostics - Rapid real-time PCR detects/quantitates M. avium subspecies in contaminated milk
Diagnostics - Real-time PCR used to quantitate uncultured bacteria in central Baltic Sea
Diagnostics - Saliva samples offer potential alternative to blood testing
Diagnostics - Seminested PCR-enzyme immunoassay is favorable method for candidemia diagnosis
Diagnostics - UG52-UC53 and 292-222 primer pairs most appropriate for Echovirus detection
Drug Development - Brazilian researchers hope to turn rattlesnake poison into potent pain killer
Drug Development - Inhibitor design wraps packing defects in HIV-1 proteins
Drug Development - Novel HIV-1 integrase inhibitor has potent antiviral activity
Drug Importation - Governor tries to sell Illinoisans on drug import program
Emergency Preparedness - Emergency plans needed in event of bioterrorism or natural epidemic
Environmental Health - Officials warn gold panners in filthy Manila river
Environmental Health - Pennsylvania doctor criticizes state health department study
Finance - Pharma company increases Vidaza sales guidance
Food-Borne Illness - E. coli O157:H7 uses different acid resistance systems
Foodborne Pathogens - Pathogenic enteric viruses persist in marinated mussels despite acid conditions
Foodborne Pathogens - Storage temperature affects ability of Streptococcus pyogenes to grow in food
Fundraising - Social awareness stamp for sickle cell disease introduced
Fungal Research - Gene essential for A. fumigatus growth but does not contribute to pathogenicity
Fungal Toxin - Fumonisins detected in herbal tea and medicinal plants in Turkey
Gastric Cancer - EBV-gastric carcinoma pathogenesis different in intestinal or diffuse EBV-GC
Gene Therapy - Break repair protein endo-exonuclease is a therapeutic target for cancer
Genomics - Short tandem repeat analysis monitors chimerism following bone marrow transplant
Graft-Versus-Host Disease - Denileukin diftitox tolerable and active in steroid-refractory acute GVHD
Graft-Versus-Host Disease - Donor CD8+ T cell-mediated TAA-specific antitumor response driven by GVHD
HIV/AIDS Immunology - CD25+/CD4+ cells associated with favorable clinical markers of HIV status
HIV/AIDS Immunology - Immune activation set point is established early in HIV infection
HIV/AIDS Research - APOBEC3F properties/hypermutation preferences indicate activity against HIV-1
HIV/AIDS Research - Fibronectin fragments stimulate transendothelial migration of HIV-1-infected MNL
HIV/AIDS Research - HIV-1 and MLV Gag sufficient to recruit APOBEC3G into virus-like particles
HIV/AIDS Research - HIV-1 gp120 decreases NO-dependent cyclic GMP accumulation in brain astroglia
HIV/AIDS Research - LAMPS of M. fermentans/M. penetrans activate HIV LTR through Toll-like receptors
HIV/AIDS Research - Mutations alter capsid protein assembly rate without changing monomer stability
HIV/AIDS Screening - Biotech receives U.S. FDA approval for HIV test with finger stick whole blood
HIV/AIDS Therapy - Drug-resistant HIV mutants higher in PBMC than plasma after changes in ART
HIV/AIDS Therapy - HIV phenotypic/genotypic markers of resistance evaluated at virologic failure
HIV/AIDS Therapy - New HIV technologies alter the nature of HIV medicine materially and socially
HIV/AIDS Therapy - Novel anti-HIV drug candidate targets CD4 lymphocytes
HIV/AIDS Therapy - Race is not associated with pharmacokinetics of nevirapine
HIV/AIDS Therapy - d4T treatment enhances mitochondrial oxidative stress
HIV/AIDS-Associated Infection - CD8+ T cells specific for EBV/CMV/FLU activated during primary HIV infection
Head and Neck Cancer - Fixing anemia doesn't improve survival for head and neck cancer patients
Helicobacter Pylori - H. pylori RpoB polymorphism correlates with differential induction of IL-8
Helicobacter Pylori - Helicobacter pylori virulence genes are associated with peptic ulcer disease
Hematology - High molecular weight hydroxyethyl starch solution stimulates platelets
Hematopoiesis - Hematopoietic cells and osteoblasts derived from common BM progenitor cell
Herpesvirus - vGPCR target gene expression drastically curtailed by host shutoff
Hormone Replacement Therapy - Estrogen plus progestin associated with increased risk of venous thrombosis
Hormone Replacement Therapy - Perioperative HRT not a risk factor for thrombosis after hip and knee surgery
Hormone Replacement Therapy - Study shows hormone pills linked to blood clots in the legs and lungs
Human T Cell Leukemia Virus - Expression of CCL5/RANTES elevated in adult T-cell leukemia cells
Hypertension - Nurses group addresses national health crisis: Uncontrolled high blood pressure
Imaging - Research at Beth Israel Deaconess broadens application of multidetector CT
Immunology - Natural toxin induces preferential and prolonged deletion of innate-like B cells
Immunology - Washington state cord blood program announces hospital partner
Immunology - vIRF3 regulates immune system and apoptosis via NF-kappaB activity inhibition
Legal Issues - Court rules that kidney failure is a disability
Legal Issues - U.S. Appeals Court overturns lower court on HDL testing infringement
Leptospirosis - Dominant leptospire genotype associated with outbreak clusters in India
Leukemia - $5 million grant targets leukemia drug development, creates new jobs
Leukemia Therapy - High-dose cytosine arabinoside/etoposide + TBI feasible in HSCT for ALL
Listeria Outbreak - L. monocytogenes infectivity in farm animals may be associated with subtypes
Liver Cancer - Liver cirrhosis prognosis determined after first hepatic encephalopathy episode
Lung Cancer - Myotubularin-related protein suppresses growth of lung carcinoma cells
Lymphoma - Lymphoma risk does not rise with chronic exposure to 50 Hz magnetic fields
Mesothelioma - High proportion of mesothelioma in South Africa from asbestos exposure
Microbial Resistance - Fluoroquinolone use predicts rates of resistant Pseudomonas aeruginosa
Multiple Myeloma - sNDA submitted for Velcade as second-line treatment in multiple myeloma
Mycobacterium - Elevation of MAC variants to Mycobacterium chimaera sp. nov is proposed
Mycobacterium Infection - Macrolide-containing regimens 55% successful in MAC lung disease
Myocardial Infarction - Patients who get blood transfusions in hospital have higher mortality
Neutropenia - G-CSF does not improve morbidity/mortality in febrile neutropenia
Norovirus - Ethanol and bleach insufficiently inactivate norovirus model
Noscomial Infection - Hospital-acquired C. difficile infection 1300-fold higher than in community
Oncology Research - Constant light exposure increases cancer incidence and decreases lifespan
Parasitic Infection - Furamidine analog markedly potentiates activity against T. cruzi/L. amazonensis
Parasitic Infection - Smoker airflow obstruction severity correlates with Pneumocystis colonization
Parasitic Infection - ap65 gene silencing reduces vaginal epithelial cells adherence by T. vaginalis
Pediatric Pneumonia - Oral amoxicillin/parenteral penicillin equal in children with severe pneumonia
Product Licensing - FibroGen to license erythropoietic small molecule in development for anemia
Product Licensing - License application submitted for HIV-1 and hepatitis C, B screening assay
Prostate Cancer - Genomic difference found in prostate cancers between Japan and Western countries
Prostate Cancer - Neuroendocrine differentiation evaluation recommended in prostate cancer
Protozoal Disease - cAMP signaling in kinetoplastid protozoa useful target for antiparasitic drugs
Quality Assurance - Health experts support partnership for improved prevention, care of DVT
Renal Transplantation - Pharmacologic responses to methylprednisolone differ by sex
Retrovirus Research - TRIM5 alpha mediates postentry block to N-tropic murine leukemia viruses
Stem Cell Research - Advances in stem cell therapy for diabetes, new patent filing announced
Stem Cell Research - CD56-expressing cells appear to contain multipotential stem cells
Stem Cell Research - Gene expression profiles analyzed during CD4+ T cell differentiation
Stem Cell Research - Lung side population cells are derived from the bone marrow
Stem Cell Research - PECAM-1 is expressed on hematopoietic stem cells throughout ontogeny
Stem Cell Research - TGF-beta 1 stimulates matrix metalloproteinase production by corneal cells
Stem Cell Research - Transplanted CNS cells survive/migrate/differentiate in ischemic cerebral cortex
Stem Cell Transplantation - Allogeneic HSCT induces remission of severe and refractory rheumatoid arthritis
Stem Cell Transplantation - Early CNS complications follow reduced-intensity stem cell transplantation
Stem Cell Transplantation - Stem-cell transplants may be used to repair peripheral nervous system
Stomach Cancer - Protein kinase C theta may be novel therapeutic target for GI stromal tumors
Tissue Engineering - Chondrocyte expansion on matrix monolayers does not prevent dedifferentiation
Tissue Storage - CordLife opens second tissue processing and storage facility in Singapore
Transplant Medicine - Georgia congressman has lung transplant surgery
Tumor Suppressor Gene - TES is the best candidate tumor suppressor gene at chromosome arm 7q31
Vector-Borne Pathogens - Concurrent infections with vector-borne pathogens caused fatal hemolytic anemia
Virology - JC virus genotypes 3 and 7 identified in South African patients
Virology - RNA viruses alter vector host range, resulting in potential disease emergence
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