Hematology
High molecular weight hydroxyethyl starch solution stimulates platelets
Published in Blood Weekly, October 28th, 2004
"Physicochemical characteristics of hydroxyethyl starch (HES) molecules determine their side effects on hemostasis. Our aim in the present experiments was to test the antiplatelet effect of novel high molecular weight HES. Citrated whole blood was hemodiluted in vitro (0% and 20%) with HES 550 (Hextend), HES 600 (6% Hetastarch-Baxter), HES 200 (Elohast), or the solvent of Hextend in its commercially available solution. The availability of glycoprotein IIb-IIIa was assessed on nonstimulated and on agonist-induced platelets using flow cytometry," researchers in Austria report.
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Source: Blood Weekly (2004-10-28)
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