Cardiopulmonary Bypass
Ketamine inhibits perioperative platelet activation in baboon CPB model
Published in Blood Weekly, November 11th, 2004
Researchers in the United States conducted a study "to investigate the effects of antifactor D monoclonal antibody (mAb) 166-32 on platelet activation during and after" hypothermic CPB "in baboons."
"Fourteen baboons (mean weight, 15 kg) underwent hypothermic CPB. Seven of them were treated with a single injection of antifactor D mAb 166-32 (5 mg/kg) and the other seven animals were given saline as control," explained A. Undar and coauthors at Penn State University.
"Each baboon was sedated with an intramuscular injection...
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Source: Blood Weekly (2004-11-11)
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