HIV/AIDS Drug Resistance
Multidrug-resistance in primary HIV infection leads to superinfection
Published in Blood Weekly, November 11th, 2004
According to a study from Canada, "the authors previous studies documented persistence of multidrug resistance (MDR) acquired in five primary HIV-1 infection (PHI) cases for 1-2 years in the absence of antiretroviral treatment. This study characterizes the evolution of transmitted wild-type (WT) (n=15), resistant (n=10), and MDR (n=6) infections."
"Longterm persistence of MDR infections (2-7 years), leading to one observed MDR superinfection is documented. Genotypic changes in circulating viral quasi-species were evaluated over 1.5-7 years in patients (n=31)...
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Source: Blood Weekly (2004-11-11)
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