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Ischemia/Reperfusion

Olive oil polyphenols are possible therapeutic tools for treatment of CHD

Published in Blood Weekly, November 11th, 2004

Oleuropein prevents oxidative myocardial injury induced by ischemia and reperfusion.

"The potential protective effects of oleuropein, a dietary antioxidant of olive oil, has been investigated in the isolated rat heart. The organs were subjected to 30 minutes of no-flow global ischemia and then reperfused. At different time intervals, the coronary effluent was collected and assayed for creatine kinase activity as well as for reduced and oxidized glutathione," scientists in Italy report.

C. Manna and colleagues of the University Naples wrote, "In addition, the extent of lipid peroxidation was evaluated by measuring thiobarbituric acid reactive...

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