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Stem Cell Research

Differentiated skeletal muscle stem cells protect renal function after ischemia

Published in Blood Weekly, November 18th, 2004

Differentiated skeletal muscle stem cells protect renal function after ischemia.

According to a study from the United States, "We previously demonstrated that endothelial cells are severely damaged during renal ischemia-reperfusion and that transplantation of adult human endothelial cells into athymic nude rats subjected to renal ischemia resulted in a dramatic protection of the kidney against injury and dysfunction.

"Morphological studies demonstrated the engraftment of transplanted cells into renal microvasculature. The goal of the present study was to determine the potential efficacy of in vitro expanded skeletal muscle-derived stem cells (MDSC)...

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