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Burn Injury

BM neutrophil production and release significantly increased after burn injury

Published in Blood Weekly, November 18th, 2004

Bone marrow neutrophil production and release is significantly increased after a burn injury.

According to recent research published in the journal Annals of Biomedical Engineering, "Production rates of blood cells from the bone marrow (BM) can be determined from pool size and residence time in the circulation only during steady state. We describe a method to evaluate changes in BM neutrophil production following severe injury."

"Male CD-1 mice underwent nonlethal cutaneous burn injury, a lethal burn injury with Pseudomonas aeruginosa infection, or sham treatment, and received bromodeoxyuridine (BrdU) to label proliferative...

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