Congenital Hypothyroidism

High prevalence of parental consanguinity in infants with permanent CH

Published in Blood Weekly, November 25th, 2004

There is a high prevalence of parental consanguinity in infants with permanent congenital hypothyroidism.

"To determine the incidence of permanent congenital hypothyroidism (CH) in Tehran and Damavand, cord blood spots were collected from February 1998-August 2002 and infants with TSH {{>=}}20 mU/l were recalled.

"CH was confirmed in neonates (aged {{>=}}7 days) with serum TSH >10 mU/l and T-4 <84 nmol/l. Cases were followed up until September 2003," scientists writing in the Journal of Pediatric Endocrinology & Metabolism report.

"Dysgenesis was detected by thyroid imaging. In eutopic cases," said A. Ordookhani...

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Source: Blood Weekly (2004-11-25)

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