Susan Hasty, Publisher
Table of Contents . . . December 2nd, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Blood Weekly | Other Publications
Cardiac Biomarker - Cardiac troponins/NT-proBNP prognostic of amyloidosis PBSCT survival
Ganciclovir - Ganciclovir less toxic to myeloid SCs from cord blood than from bone marrow
Tissue Engineering - Hyaluronic acid-based scaffolds may stimulate heart valve tissue formation
Tissue Regeneration - Novel system allows characterization of scaffolds for soft tissue regeneration
Umbilical Cord Blood - Novel cord blood cells identified with hematopoietic/chondrocytic potential
AL Amyloidosis - High-dose melphalan and ASCT improves quality of life of AL amyloidosis patients
Acute Lymphoblastic Leukemia - Advances in ALL treatment may lead to elimination of irradiation
Acute Myelogenous Leukemia - AML samples with FLT3/ITD mutations preferentially killed by FLT3 inhibition
Acute Myeloid Leukemia - Idarubicin and busulfan feasible for elderly AML patients undergoing ASCT
Anti-inflammatory Effects - Inhaled CO has anti-inflammatory effects against ventilator-induced lung injury
Apoptosis - M4N induces growth arrest/apoptosis by inhibiting Cdc2 and survivin expression
Aspergillosis - Aspergillosis: Emerging infection in critically ill patients without malignancy
Bacterial Resistance - Indian Salmonella Typhi isolates have reduced ciprofloxacin susceptibility
Bacteriology - Pneumococcal virulence factor contributions to pathogenesis studied in mice
Basal Cell Carcinoma - Basal cell carcinoma rates continuously increasing in the Netherlands since 1973
Biotechnology - MTT/ATP/calcein assays similarly predict potency of cytotoxic anticancer agents
Blood Collection - Company enters blood-bank market with new Lasette
Bone Marrow Failure - Murine model developed for bone marrow failure
Bone Marrow Transplantation - Suicide gene constructs may be effective graft-versus-leukemia therapy
Breast Cancer - Antiestrogenic DTACs inhibit estrogen receptor alpha-mediated transcription
Burkholderia Cepacia - No correlation between B. cepacia complex wbiI RFLP genotype and species
Burkitt Lymphoma - Intensive/short-term Burkitt lymphoma chemotherapy effective/manageable toxicity
Business & Finance - ATryn maker reports third-quarter net loss of $7.2 million
Business & Finance - Haemonetics makes equity investment, enters research collaboration
Calcivirus Inactivation - Nonionizing and ionizing radiation inactivate Calicivirus
Cancer Vaccine - PHB1/PHB2 identified as blood-borne tumor antigens
Cardiopulmonary Bypass - Deleterious hematological effects of CBP centrifugal pumps compared
Cardiovascular Health - Thrombin inhibitor used in coronary intervention lowers costs, study shows
Celiac Disease Epidemiology - Celiac disease prevalence higher in Turkish population compared to Western world
Central Nervous System Disease - Stem cell focused biotech completes equity financing to support clinical trial
Cigarette Smoke - Low levels of cigarette smoke induce irreversible change in cell chromosomes
Clostridium Perfringens - Cpe-positive Clostridium perfringens spores from feces isolated/enumerated
Community-Associated Infection - Risk of community-associated MRSA infection is associated with several factors
Coronary Angioplasty - Thrombolytic therapy and angioplasty can effectively achieve cardiac reperfusion
Cytomegalovirus Infection - Oral valganciclovir equivalent to oral ganciclovir for CMV prevention
Diagnostics - Lab designer's hematology analyzers ranked best in industry by consulting firm
Diagnostics - LightCycler PCR assay detects/characterizes enterotoxigenic Escherichia coli
Dialysis - Medical equipment, renal device companies partner to manufacture dialysis system
Ebola Virus - Blood samples from fatal and nonfatal cases of Ebola infection analyzed
Enzymology - Virus-mediated therapy corrects acute intermittent porphyria in murine models
Erythropoietin - Transgenic EPO expression overcomes lethality caused by c-Kit(w/w) mutation
Familial Amyloidotic Polyneuropathy - Successful fatherhood, pregnancy possible for liver-transplanted FAP patients
Finance - Dialysis company reports Q3 income of $55.3 million
Graft-versus-Host Disease - Cyclosporin and MMF for GVHD prophylaxis associated with faster engraftment
Graft-versus-Host Disease - Valpha24+ NK cell number after HSCT may be related to the development of GVHD
HIV/AIDS & Tuberculosis - HIV has less effect on point prevalence of TB disease than on TB incidence
HIV/AIDS & Tuberculosis - Strategy developed to decrease global burden of TB/HIV
HIV/AIDS Diagnostics - Rapid field test sensitive and specific for detecting/differentiating HIV types
HIV/AIDS Diagnostics - Simple and reproducible assay developed to screen HIV-1 subtypes
HIV/AIDS Immunology - Persistent immune deficit in some patients irrespective of HIV viral load
HIV/AIDS Infection - Association between dual HIV-1 infection and elevated viral load set point
HIV/AIDS Pathogenesis - Toll-like receptor 2 stimulation may contribute to HIV immunopathogenesis
HIV/AIDS Research - E. bieneusi genotype D spores transmitted to SIV-infected macaques
HIV/AIDS Research - HIV-1 viral load not associated with intrapatient quasispecies heterogeneity
HIV/AIDS Research - Heat-shock protein 70 coprecipitates with Vpr from HIV-1-infected macrophages
HIV/AIDS Research - High-throughput assay identifies CCR5/CD4-mediated HIV virus entry inhibitors
HIV/AIDS Screening - Chinese blood centers to use rapid HIV Tests
HIV/AIDS Therapy - HIV-1 integrase nuclear import inhibited by styrylquinoline derivatives
HIV/AIDS Therapy - Lopinivir efficacy decreases following cotransfection of wild-type HIV clones
HIV/AIDS Therapy - Protease inhibitor fosamprenavir potent against advanced HIV disease
HIV/AIDS Therapy - Trim5-cyclophilin A fusion protein from owl monkey kidney cells restricts HIV-1
HIV/AIDS-Related Apoptosis - Altered TNFSF CD95 receptor expression reduces B cell survival in HIV infection
HIV/AIDS-Related Drug Resistance - Wild-type breast cancer resistance protein induces cellular resistance to NRTIs
HIV/AIDS-Related Infection - Protothecal arthritis and tenosynovitis resulted from hematogenous dissemination
HIV/AIDS-Related Transmission - HIV viral load increases in breast milk following ZDV discontinuation
Heart Failure - Patients with heart failure on coumarin should be closely monitored
Helicobacter Pylori - IL-1 receptor-1 gene polymorphism associated with increased H. pylori risk
Hematology - Imatinib does not normalize blood dendritic cell levels in leukemia patients
Hematopoiesis - DC production in myelodysplastic syndrome results in ineffective dendritopoiesis
Hemochromatosis - IgG treatment in pregnancy reduces severity of rare liver condition in newborns
Hemophilia - Factor IX launched for the treatment of hemophilia B in Spain
Hepatitis B - European authorities give positive opinion for Fendrix vaccine
Hepatitis Therapy - Drug combination shows promise in treating hepatitis C
Immunology - CD46-mediated costimulation enhances early TCR/CD3 signaling in CD4+ cells
Influenza A Pathogenesis - Hemagglutinin of 1918 pandemic influenza A virus confers enhanced pathogenicity
Inotropic Support - Report describes the keys to weaning patients from inotropic support.
Invasive Aspergillosis - Lower cut-off proposed for galactomannan detection in neutropenic/SCT patients
Ischemia - Generation of NO from NO2 by xanthine oxidoreductase protects the myocardium
Kaposi Sarcoma-Associated Herpesvirus - Kaposi sarcoma-associated herpesvirus transmission likely via saliva
Kidney Stem Cells - Renal papilla is a niche for kidney stem cells
Kidney Transplantation - Abnormal relapse of atypical hemolytic uremic syndrome described
Klebsiella Pneumoniae - Intubation/prematurity risk factors for neonatal K. pneumoniae infection
Leishmaniasis - Zymodemes identified from isoenzyme analysis of Leishmania strains in France
Leukemia - Leukemic fusion gene AME suppresses CEBPA in AML by calreticulin activation
Leukemia - Researcher studying new form of anticancer drug resistance in leukemia cells
Leukemia - Risk of blood cancer high in older obese women
Leukemia Therapy - Gemtuzumab ozogamicin effective in relapsed APL patients
Liposomal Delivery - Novel RGD lipopeptides target liposomes to integrin-expressing melanoma cells
Liver Transplantation - Hemodynamic factors limit the outcomes of liver candidates with low MELD scores
Lymphoma - Higher survival with BEAM conditioning regimen over CEB in lymphoma patients
Melanocytes - PI3K mediates protection against TRAIL-induced apoptosis in melanocytes
Melanoma - Lonidamine plus radiation increase melanoma cell apoptosis
Melanoma - Melanoma cell TRAIL resistance reversed by UVB radiation via FLIP downregulation
Meningococcal Epidemiology - New genetic lineages of Neisseria meningitides W135 continue to emerge
Mycobacterial Disease - Inhaled IFN-gamma effectively treats non-TB mycobacterial pulmonary disease
Mycobacterium Tuberculosis - Beijing/W lineage of M. tuberculosis defined on the basis of genetic markers
Myelodysplastic Syndromes - Reduced-intensity conditioned HSCT is safe/effective in myelodysplastic patients
Neocortex Genes - Genes expressed in the upper layers of the neocortex are identified
Neural Stem Cell Research - Neural SC REST/NRSF gene activation sufficient to cause neuronal differentiation
Neural Stem Cell Research - Neural SCs promote axon regrowth via cellular guidance after spinal cord injury
Norovirus Outbreak - Alterations to norovirus capsid structure explains 2002-2003 outbreaks
Personnel - Life sciences company names member to board of directors
Personnel - Valeta A. Gregg, PhD, JD, elected to bio products company board of directors
Programmed Cell Death - Apoptotic death in B- and T-lymphocytes can be quantified with a new assay
Proteomics - Proteomics used to identify markers for diagnosis of enteric pathogens
Public Health - Public health emergency response information system developed in China
Respiratory Syncytial Virus - IFN-gamma reduced in children with severe respiratory syncytial virus infection
SARS Outbreak - Different SARS epidemic curves reveal similar impacts of control measures
Salmonella Outbreak - Restaurant patrons sickened by chef infected with drug-resistant S. typhimurium
Septic Shock - A readily available marker to predict mortality in septic shock is needed
Sexually Transmitted Disease - A few HIV-infected men in Australia are still having unprotected sex
St. Louis Encephalitis Virus - Springtime drought facilitates St. Louis encephalitis virus amplification
Stem Cell - Paper published on the origin and function of skin-derived precursors
Stem Cell Research - Biotech company comments on California initiative to support stem cell research
Stem Cell Research - Chemicon International acquires mouse embryonic stem cell product lines
Stem Cell Research - Endocrinologists see hope for stem-cell use as diabetes cure
Stem Cell Research - Engineered stem cells can home in on tumors and deliver drug payload in mice
Stem Cell Research - High-affinity receptor for IgE on dendrites modified by TGF-beta1 concentration
Stem Cell Research - Mastermind critically regulates Notch-mediated lymphoid cell fate decisions
Stem Cell Research - Mood stabilizer valproic acid stimulates forebrain SC GABA neurogenesis
Stem Cell Research - The artery wall is a source of progenitor cells that have regenerative potential
Stem Cell Transplantation - HSCT patients at moderate risk for developing supraventricular tachyarrhythmias
Stem Cell Transplantation - IL-7 does not effect immunological reconstitution after HSCT
Stem Cell Transplantation - Nonmyeloablative ASCT decreases treatment-related mortality
Stem Cell Transplantation - Survival rates following HSCT higher in pediatric than adult transplant centers
Stem Cell Transplantation - Targeted host lymphocyte depletion facilitates TCD allograft engraftment
Streptococcus Pyogenes - S. pyogenes recovered from scarlet fever patients molecularly characterized
Synthetic Blood - Red blood cell substitute in trials with Virginia Commonwealth for U.S. Navy
Testicular Cancer - Increased PCB congeners found in blood of mothers of sons with testicular cancer
Thiotepa Conditioning Regimen - Thiotepa conditioning regimen associated with renal and hepatic toxicity
Thrombosis - Cholesterol-lowering drug may also reduce risk of blood clots
Tissue Engineering - Bone-like tissue engineered using bone marrow stem cells and silk scaffolds
Tissue Engineering - PLGA and PLGA/chitin matrices are good matrices for normal fibroblasts
Tissue Engineering - Three-dimensional polymeric scaffolds developed for soft tissue engineering
Tuberculosis - Genetic susceptibility to tuberculosis in Africans is polygenic
Tuberculosis - Serum IgE levels higher in tuberculosis patients coinfected with HIV/parasites
Tumor Suppressor Gene - Thyroid hormone receptor beta gene functions as tumor suppressor gene
Vibrio Vulnificus - Pulsed-field gel electrophoresis used to analyze Vibrio vulnificus strains
Viral Gastroenteritis - Norovirus and sapovirus infection detected in children with gastroenteritis
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