Susan Hasty, Publisher
Table of Contents . . . December 16th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Blood Weekly | Other Publications
Cord Blood - IL-15 enhances cytotoxicity/receptor expression/neonatal NK cell expansion
Embryonic Development - Multiple functions of Jab1 required for early embryonic development
HLA Typing - High-resolution class I HLA typing may optimize donor selection/improve outcome
Tissue Engineering - Acellular liver matrix improves survival and function of cultured hepatocytes
Tissue Engineering - Heparin conjugated polylactide may be applied as blood compatible material
Acute Myeloid Leukemia - Dual-specificity fusion toxin selective and potent agent for AML treatment
Aldosteronism - Increased primary aldosteronism prevalence reflects increased screening tests
Animal Studies - Mice produce transgenic progeny after in vivo germ line stem cell transduction
Anthrax - Drug demonstrates survival benefits when given after anthrax exposure
Anticoagulants - Potential decrease in thromboembolism must be balanced against bleeding risk
Antimicrobials - Novel compounds have antiretroviral and antibacterial activity
Antithrombotics - Report presents strategies for implementing thrombosis management guidelines
Antithrombotics - Report provides guidelines for the use of vitamin K agonists
Apoptosis - Rituximab/alemtuzumab induce caspase-independent apoptotic pathway in CLL cells
Avian Cholera - Wetlands an unlikely reservoir for the bacteria that causes avian cholera
Biological Therapy - Autologous antitumor lymphocytes regress metastatic melanoma in cancer patients
Brucellosis & Q Fever - Brucellosis/Q fever seroprevalence determined in Central African Republic cattle
COX-2 Inhibitor - RNA-binding protein CUGBP2/COX-2-mediated PGE2 antagonistic in radiation damage
Cancer Therapy - Enzon, partner announce the filing of a new drug submission to Health Canada
Cardiology - New document outlines training and credential standards for carotid stenting
Chlamydia - Novel high-throughput assay screens antichlamydial activity
Chronic Lymphocytic Leukemia - Novel DNA cross-linking agent has potent/selective cytotoxicity in CLL B cells
Collaborations - Golden Hand Resources enters stem cell agreement with Ramot
Creutzfeldt-Jakob Disease - Survival predicted by correlates in sporadic Creutzfeldt-Jakob disease
Cytomegalovirus - Two pasteurization methods inactivate CMV in breast milk
Deep Vein Thrombosis - Pycnogenol offers protection from thrombotic events during prolonged air travel
Diabetes Risk - Asian Indians have low risk threshold for acquired diabetogenic factors
Diabetes Therapy - Data presented human embryonic stem cell based therapy for diabetes
Diagnostics - G-CSF response before leukopenia predicts infection defense in HD chemotherapy
Dialysis - Non-diphtheria corynebacterial infections reported in CAPD patients
Disease Associations - Interleukin-2 receptor antibody mitigates diabetic onset in liver recipients
Disease Associations - Tetraspanin crucial for basement membrane assembly in kidney and skin
Drug Delivery - Novel semicrystalline films developed for drug delivery applications
Drug Development - Collaboration to develop controlled-release formulations of oral anticoagulant
Drug Development - European pharmaceutical company gets E.U. approval for bone marrow disorder drug
Drug Development - Novel assay screens anti-SARS drugs
Environmental Health - Blood study inquiry planned in Tar Creek case
Erythropoiesis - Human heme exporter that is essential for erythropoiesis identified
Escherichia Coli - Toxin-producing E. coli survive in foods stored at wide temperature range
Facilities - Hemophilia Foundation of Michigan moves to new facility
Factor XII Deficiency - Factor XII deficiency does not affect hemostasis
Familial Amyloidotic Polyneuropathy - ECG outcomes were related to autonomic and motor functions, not heart functions
Finance - Biotech company reports third quarter results
Food Poisoning - Polycavernoside A causes fatal food poisoning from red alga Gracilaria edulis
Gene Expression - Ag-specific PBMC gene expression profiles do not reflect those of T-cell subsets
Genetic Disorders - Alterations in the MURR1 gene are seen in patients with Wilson disease
Genetic Disorders - Oxidative stress regulation by ATM gene required for self-renewal of HSCs
Graft-versus-Host Disease - Chronic GvHD suppresses relapse in CML and ALL but not in AML
HIV/AIDS & Leishmaniasis - L. infantum enhances HIV-1 replication in MDMs through complex cytokine network
HIV/AIDS & Tuberculosis - Interference with endosomal sorting machinery contributes to AIDS/TB synergism
HIV/AIDS Drug Adherence - Several factors predict virologic success in antiretroviral adherence program
HIV/AIDS Epidemiology - Median CD4 lymphocyte counts are low in HIV-uninfected adults in Botswana
HIV/AIDS Healthcare - HIV-1 genotype/virtual phenotype correlate for predicting PI/NNRTI resistance
HIV/AIDS Pathogenesis - HIV-1 alone does not cause death of uninfected/latently-infected CD4 cells
HIV/AIDS Pathogenesis - Superantigen stimulation causes CD4 apoptosis in HIV-infection children on HAART
HIV/AIDS Research - CCR5 inhibitor causes transient increase in X4 virus in R5/X4-infected macaques
HIV/AIDS Research - Galantamine and nicotine inhibit HIV-1 gp120-induced microglial activation
HIV/AIDS Research - HIV-1 virion fusion assay measures virion fusion independently of uncoating
HIV/AIDS Research - RTF prevents bystander T-cell death associated with HIV infection
HIV/AIDS Research - SI viruses may hasten disease progression by perturbing T cell homeostasis
HIV/AIDS Research - Temporal HIV-1 structures detected in samples separated by 22 months or more
HIV/AIDS Treatment - HPLC method monitors atazanavir therapy in HIV-infected patients
HIV/AIDS Treatment - Mobius subfamily member kalata B1 exhibits anti-HIV activity
HIV/AIDS Treatment - Zidovudine forms DNA adducts in treated HIV-infected patients
HIV/AIDS Viral Load - Abbott LCx concordant with Roche Amplicor and Bayer bDNA HIV viral load assays
HIV/AIDS-Associated Infection - Higher CD4 counts/HAART predicts pulmonary M. kansasii/HIV infection survival
HIV/AIDS-Associated Nephropathy - HAART helps prevent progression of pediatric HIV-associated nephropathy
HIV/AIDS-Mental Health - HIV/AIDS patients beliefs vary on causal attributions of fatigue
Hair Studies - Beta-catenin/lef-1 signaling required for DP-induced hair differentiation
Heart Disease Risk - Vitamin E may help some diabetics avoid risk
Hematological Disease - Laser correlative spectroscopy assay enables early diagnosis
Hematology - Extended beta-globin locus control region elements prolong transgene expression
Hematology - Pharmacogenetics enhances the management of patients on warfarin therapy
Hematology - Techniques to evaluate erythrocyte deformability in diabetes outlined
Hematopoiesis - Activated H-Ras regulates hematopoietic cell survived by modulating Survivin
Hemophilia - OBI-1, recombinant procine Factor VIII, to enter phase II clinical studies
Hepatitis B Virus - Eisai in-licenses antihepatitis B agent clevudine
Herpesvirus Outbreak - Owner likely spreads deadly herpesvirus to colony of captive common marmosets
Hyperthyroidism - Iodine contaminants responsible for neonatal chemical hyperthyroidism in Nigeria
Immune Response - DC-T cell interactions in BM play important role in immune responses to antigens
Immunosuppression - Calcineurin inhibitors slow fibrosis progression after HCV-related liver grafts
Infection - Manufacturing agreement for staph infection treatment announced
Insulin Pump - U.S. FDA alternate site clearance helps blood glucose meter users
Ischemic Stroke - Report presents guidelines for therapeutic management of ischemic stroke
Legal Issues - Settlement to fund massive health study of water contamination
Leishmaniasis - Cutaneous leishmaniasis treated with lipid formulations of amphotericin B
Leukemia - Study: StemEx for the treatment of leukemia safe and efficacious
Leukemia - Umbilical-cord blood works well against leukemia in adults as well as children
Liver Transplantation - Short-term weight loss would expand the pool of living liver transplant donors
Lung Cancer - Long-term smokers avoid lung cancer risk if they quit smoking
Lymphoma - NK cells induce resistance to cytotoxic chemotherapy in B lymphoma cells
Malaria - Plasmodium falciparum polymorphisms analyzed from Brazilian Amazon region
Malaria - Individual malaria disease susceptibility/outbreak severity varies in Sudan
Mutagenesis - Glycophorin A is potential biomarker for mutagenic effects of pesticides
Myoblast Transplantation - Follow-up data on myoblast cell therapy for congestive heart failure presented
Myocardial Injury - Cytochrome P450omega-hydroxylases have a role in exacerbating myocardial injury
Natural Products - beta-HIVS suppresses TNF receptor-associated protein 1 gene expression
Neural Stem Cell Research - GluR2 predominantly expressed among AMPA receptor subunits in neural SCs
Neural Stem Cell Research - Pleiotrophin signaling systems involved in modulation of fate of neural SCs
Norovirus - Detergent followed by bleach/detergent reduces Norovirus contamination
Obstetrics - Guidelines address use of antithrombotics by pregnant women
Obstetrics - Preconception anemia affects pregnancy outcome in Chinese women
Oncology - Platelet activation shifts the angiogenic balance in cancer patients
Osteoporosis - Antagonizing PPARgamma activity in fat effectively combats osteoporosis
Platelet Activation - Platelet secretion pathway mediated by cGMP-dependent protein kinase
Pneumocystis Carinii - SP-A is local effector molecule in lung host defense against P. carinii
Pneumocystis Carinii Pneumonia - Suspected pediatric PCP in resource-poor settings should be treated as emergency
Prostate Cancer - Coding sequence determined for orthologs of prostate cancer susceptibility gene
Prostate Cancer - Primary tumor-derived human prostate cancer cells retain neoplastic phenotypes
Pyomyositis - Bacterial pyomyositis increasing in HIV and non-HIV infected patients in the US
RNA Research - Electroporation improves the success of embryonic stem cell transfection
Renal Cell Carcinoma - HIF1A gene polymorphisms associated with renal cell carcinoma phenotype
Respiratory Disease - Asbestos precipitates tissue factor production in lung epithelial cells
Respiratory Syncytial Virus - Bovine respiratory syncytial virus detected/quantitated by real-time RT-PCR
Respiratory Syncytial Virus - Palivizumab used to control RSV outbreak in neonatal intensive care unit
Restructuring - Pharmaceutical company announces plan to discontinue gene editing operations
Rheumatoid Arthritis - Rheumatoid arthritis inhibited by agonistic anti-4-1BB monoclonal antibody
Robotic Surgery - Surgical robot used to remove renal artery aneurysm at Canadian health center
Selenium - Bioavailable selenium not preferentially toxic to transformed hepatocytes
Septicemia - Study shows mast cells linked to asthma and eczema can help cure sepsis in mice
Stem Cell Research - Bryostatin-1 enhances maturation/antigen-presenting ability of dendritic cells
Stem Cell Research - DNA demethylation necessary for epigenetic reprogramming of somatic cell nuclei
Stem Cell Research - Gfi-1 restricts proliferation and preserves functional integrity of HSCs
Stem Cell Research - Hematopoietic stem cells are highly receptive to adenovirus type 11p
Stem Cell Research - ID/OLIG protein interactions mediate BMP4 inhibition on OL differentiation
Stem Cell Research - Informed consent recommendations offered for tissue/cell research donors
Stem Cell Research - Poll shows support for stem cell research among those who voted to re-elect Bush
Stem Cell Research - Research: Cells derived from hESCs can be immortalized by telomerase
Stem Cell Transplantation - Alpha-erythropoietin + filgrastim improves outcome/cost balance of ASCT
Stem Cell Transplantation - Megakaryocyte engraftment follows reduced-intensity conditioning
Stem Cell Transplantation - Stem cells from donors with abnormal findings can be used for HCT
Stroke - Family history predicts young women's risk of stroke
Surgical Outcomes - Blood-reduction program benefits cardiac surgery patients
Technology - U.S. HHS rates LifeTree system for tracking nation's blood supply as exceptional
Thrombocytosis - HIV/AIDS-associated thrombocytosis is associated with severe disease
Thrombosis - First international standard for common genetic test approved by WHO
Thrombosis - High levels of anxiety may affect coagulation of blood
Tissue Engineering - Bioreactor validated for engineering vocal fold tissues
Tissue Engineering - Tissue engineered stomach regenerates into complex tissue resembling stomach
Transfusion - Report provides suggestions for blood transfusions for terminal patients
Transplant Medicine - Better methods are needed to prevent or treat rejection of lung transplants
Transplant Medicine - Positive anticardiolipin antibodies were not associated with inferior outcomes
Transplant Medicine - Researchers suggest review of Chile's approach to liver-transplant waiting lists
Transplant Medicine - Study investigates the mechanisms of organ rejection
Tuberculosis - Mathematical model predicts emergence of multidrug-resistant TB 'hot zones'
Tuberculosis - Small populations of fit MDRTB strains can out-compete low fitness strains
Vancomycin Resistance - Two vancomycin-resistant E. faecium outbreaks in NICU caused by different clones
Virology - Influenza vaccination is not associated with liver transplant rejection
Yersinia Pestis - Study shows evolution of virulent Yersinia pestis epidemic clone
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