Antienteroviral Therapy
Novel compounds have potent antienteroviral activity
Published in Blood Weekly, December 30th, 2004
According to published research from Taiwan, "A series of novel, oxime ether-containing pyridyl imidazolidinones were synthesized and their antiviral activity was evaluated in a plaque reduction assay.
"It is very interesting that this class of compounds is specific for human enteroviruses, in particular, enterovirus 71 (EV71). Some derivatives strongly inhibited enterovirus replication with activities higher or comparable to those of the reference compounds such as A(1) and A(2)."
"Preliminary SAR studies revealed that the chain length of the alkyl linker and the alkyl...
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Source: Blood Weekly (2004-12-30)
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