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Tissue Engineering

Demineralized cortical bone matrix repairs osteochondral defect

Published in Blood Weekly, January 6th, 2005

Demineralized cortical bone matrix repairs an osteochondral defect.

According to recent research published in the journal Clinical Orthopaedics and Related Research, "It has been reported that demineralized bone matrix (cortical or trabecular bone) contains intrinsic cytokines.

"In the present study, we tested allogeneic demineralized bone matrix for its capacity to resurface osteochondral defects in a rabbit model with the assumption that the intrinsic cytokines in demineralized bone matrix will facilitate the recruitment of progenitor cells from bone marrow into the defect.

"It was further assumed that these intrinsic...

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