Umbilical Cord Blood
Natural killer cell receptor KLRG1 frequently expressed in cord blood T cells
Published in Blood Weekly, January 6th, 2005
"The killer cell lectin-like receptor G1 (KLRG1) belongs to the family of inhibitory C-type lectins that are encoded in the NK gene complex. Similar to other inhibitory NK cell receptors, KLRG1 expression in adult peripheral blood lymphocytes is restricted to NK cells and to antigen-experienced T cells.
"Umbilical cord blood T cells are thought to represent an homogenous pool of naive T cells. Surprisingly, we identified substantial subsets of CD4 (similar to 30%) and CD8 (similar to 20%) alphabeta T cells in cord blood that expressed KLRG1," scientists in Germany...
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Source: Blood Weekly (2005-01-06)
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