Renal Function
G-CSF accelerates regeneration/prevents renal tubular epithelial cell apoptosis
Published in Blood Weekly, January 13th, 2005
According to published research from Japan, "In this study, the effect of hematopoietic cytokines, i.e., granulocyte-colony stimulating factor (G-CSF), stem cell factor (SCF), and granulocyte-macrophage-colony stimulating factor (GM-CSF), on renal function was studied in cisplatin-induced acute renal failure in mice."
"Treatment with G-CSF significantly ameliorated both BUN and serum creatinine increase induced by cisplatin administration with concomitant alleviation in the degree of necrotic change, enhancement in DNA synthesis, and decrease in apoptosis of renal...
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Source: Blood Weekly (2005-01-13)
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