Stem Cell Transplantation
Purified NK-cell infusion consolidates engraftment after haploidentical SCT
Published in Blood Weekly, January 13th, 2005
"This pilot study tested feasibility of natural killer cell purification and infusion (NK-DLI) in patients after haploidentical hematopoietic stem cell transplantation (HSCT). The aim was to obtain {{>=}}1.0 x 107/kg CD56+/CD3- NK cells and <1.0x105/kg CD3+ T cells. Mononuclear cells were collected by 10 L leukapheresis," scientists in Switzerland report.
"A two-step ex vivo procedure was used to purify NK cells, using an immunomagnetic T-cell depletion, followed by NK-cell enrichment. Five patients with high-risk...
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Source: Blood Weekly (2005-01-13)
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