Apoptosis
Alpha-DL-tocopherol protects ESFT cells from betulinic acid-induced apoptosis
Published in Blood Weekly, January 13th, 2005
"Betulinic acid (BA) is known to induce apoptosis in melanoma neuroectodermal and malignant brain cancer cell lines. Present report describes the role of antioxidants on the BA-induced toxicity to human cell line SK-N-MC.
"Hydrophilic antioxidants viz, L-ascorbic acid (VitC) and N-acetyl-L-cysteine (L-NAC) had no protective effect on BA-induced apoptosis at the maximal concentrations tested," scientists writing in the journal Toxicology Letters report.
"The lipophilic antioxidant, alpha-DL-tocopherol (VitE) showed a...
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Source: Blood Weekly (2005-01-13)
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