Published in Blood Weekly, January 13th, 2005
"Hexadecylphosphocholine (HePC, Miltefosine) is an antitumor phospholipid and known inducer of apoptosis in human breast cancer cells. The mechanism underlying the induction of cell death by HePC, however, is not clear yet. In this study, we have investigated the cytotoxic effects of HePC on canine mammary tumor cells (CMTs) in vitro," scientists in the Netherlands report.
"Upon addition of HePC," said D. Diujsings and coworkers, "CMTs rapidly exhibited several features that resembled apoptotic cell death. Cells showed externalisation of phosphatidylserine, a hallmark of...
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