Stem Cell Transplantation
Routine high resolution HLA-A/B/C typing does not improve HSCT outcome
Published in Blood Weekly, January 13th, 2005
According to recent research published in the journal Transplantation, "At our institution the selection of unrelated donors for hematopoietic stem cell transplantation (HSCT) relies on low resolution human leukocyte antigen (HLA)-A,B and high resolution HLA-DRB1, DQB1 DNA-based typing.
"To answer the question of whether routine high resolution HLA-A,B,C typing might improve HSCT outcome, 171 white 'HLA-identical' donor/recipient pairs, as stated by our pretransplant tissue typing routine, were retyped for HLA-A,B,C using sequence based...
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Source: Blood Weekly (2005-01-13)
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