Blood Weekly

Embryonic Stem Cell Research - Genes identified that are enriched in embryonic stem cells

Neural Stem Cell Transplantation - Neural SCT promotes long-term functional recovery after traumatic brain injury

Protein Signaling - Transcriptional activity of Smad proteins in development monitored in vivo

Tissue Engineering - Cartilage-like tissue engineered with mesenchymal SCs and silk protein scaffolds

Wound Healing - BM-derived cells contribute to epithelial engraftment during wound healing

Antiretroviral Therapy - Drug-dependent HIV-1 variant emerges during T20 fusion inhibitor therapy

Antiretroviral Therapy - Novel sesterterpenes isolated from Madagascan sponges inhibit HIV-1 RT

Antitumor Therapy - Bacteriolytic therapy generates immune response against experimental tumors

Blood Banking - Cord blood bank wins legal victory

Blood Substitute - Effect of sol-gel encapsulation on hemoglobin oxygen binding determined

Bone Marrow - Theoretical model predicts bone marrow response during hemorrhagic shock

Burkholderia Cepacia -  Burkholderia cepacia complex isolated from hemodialysis unit outbreak

Burn Injury - Burn injury/HIV infection/sepsis independently result in immunosuppression

Business Update - Biopharma company prepared to select manufacturer for PHER-O2.

Business Update - Pharma company specializing in coagulation disorders enters Australian market

C-Reactive Protein - C-reactive protein levels are influenced polymorphism of LT Alpha

Cancer Research - Biopharma company initiates phase I trial for MGCD0103

Cancer Research - New drug fights blood cancer patients' mouth and digestive tract mucositis

Cancer Research - Research shows drug combination promising for leukemia treatment

Cancer Therapy - Company expands oncology pipeline with product candidates from the NCI, PHS

Candidemia - Candidemia is rare in allogeneic stem cell transplantation recipients

Candidiasis - Non-albicans Candida spp. emerging as important pathogens in neonatal ICUs

Cardiac Hypertrophy - Cardioprotective effects of drugs may deteriorate in hypertrophied hearts

Cardiac Reperfusion - Content of cytochrome c in cytosol increases exclusively during reperfusion

Cholesterol Management - Attitudes of physicians and consumers differ about prescription medications

Chronic Myelogenous Leukemia - Tyrphostin AG1024 may be basis of novel therapy for STI571 refractory CML

Clinical Trials - Companies sign agreement to develop process to make enzyme for conversion study

Complementary and Alternative Medcine - Complementary and alternative medicine use prevalent among HIV-infected women

Complementary and Alternative Medicine - L-carnitine and acetyl-L-carnitine promising for HIV-related complications

Dengue Virus - American/Asian dengue 2 virus genotype introduced into Yucatan State of Mexico

Dengue Virus - Genome from severe 2001 dengue-1 epidemic in French Polynesia characterized

Dengue Virus - Mosquitoes contribute to evolutionary conservation of dengue virus

Development - Phosphorylation regulates cell growth and kinase stability and activation

Diagnostics - Rapid bioassay using bioconjugated nanoparticles detects single bacterial cell

Diagnostics - Real-time PCR quickly/accurately detects S. enterica and E. coli O157:H7

Dialysis - Dialysis company awarded British Columbia Provincial contract

Drug Development - EviMed company announces new diagnostics for sepsis and acute renal failure

Drug Development - Structural model assists in rational design of NRTIs with higher specificity

Drug Resistance - Dissemination of E. coli producing CMY-11 due to cephamycin-resistant outbreaks

Drug Screening - Computational methods 'virtually' screen drugs such as protease inhibitors

Echovirus - Echovirus 13 outbreak presented as viral meningitis in Lithuanian children

Embryonic Stem Cell Research - TGF-beta 1 signaling contributes to development of smooth muscle cells from ESCs

Endothelial Progenitor Cells - Hierarchy of EPCs is based on clonogenic and proliferative potential

Enterovirus - Enterovirus 71 infection induces endothelial cell activation and apoptosis

Epidemics - Probabilistic model demonstrates ability to forecast spread of epidemics

Epidemiology - Researchers collect data on Arizona town's leukemia

Escherichia Coli - Enzyme-linked immunomagnetic chemiluminescence detects E. coli 0157:H7 in beef

Finance - Cell Therapeutics inks TRISENOX financing agreement

Finance - Hawaii-based biopharma company awarded $15.5 million in NIH funding

Gene Expression - Bioscience company introduces PCR-based DNA microarray data verification system

HIV/AIDS Antiretroviral Therapy - Novel pyrrolidone-based HIV-1 protease inhibitors developed

HIV/AIDS Epidemiology - HIV-1 sub-subtype A3 circulating in Senegal since 1988

HIV/AIDS Epidemiology - Novel Bayesian method reconstructs known HIV-1CRF04_cpx transmission network

HIV/AIDS Pathogenesis - Mitochondrial regulation of apoptosis affects HIV pathogenesis and treatment

HIV/AIDS Pathogenesis - Proliferating HIV-1-specific CD4 cells inversely associated with plasma viremia

HIV/AIDS Research - Budding defect of HIV matrix mutants reversed with additional 107-matrix codons

HIV/AIDS Research - CpG oligodeoxynucleotides block HIV-1 replication in lymphoid tissue

HIV/AIDS Research - HIV-1 Gag expression modulates ligand-induced downregulation of EGF receptor

HIV/AIDS Research - HIV-1 double-helix destabilization near cleaved bond promotes 3'-end processing

HIV/AIDS Research - HIV-1 triggers mitochondrion death

HIV/AIDS Research - Multiple residues in CCR3 extracellular domains critical for coreceptor activity

HIV/AIDS Research - NF-kappaB/c-Jun LTR binding in G₂ -arrested cells required for CBP recruitment

HIV/AIDS Research - Novel approach analyzes mitochondrial toxicity induced by NRTIs

HIV/AIDS Research - Novel system allows site/subunit-specific unnatural AA incorporation into HIV-RT

HIV/AIDS Research - Tat-induced IL-10 production depends on PKC beta(II)/delta isozyme activation

HIV/AIDS Therapy - Enhancing ceramide levels inhibits HIV infection

HIV/AIDS Therapy - Novel tetrameric analog of indolicidin potent inhibitor of HIV-1 integrase

HIV/AIDS-Associated Infection - Widespread and invasive Trichophyton rubrum infection mimics KS in AIDS patient

HIV/AIDS-Associated Lipodystrophy - Uncoupling proteins have potential role in HIV lipodystrophy

HIV/AIDS-Associated Wasting Syndrome - Lipoatrophy pathogenesis attributed to mitochondrial toxicity of NRTIs

HIV/AIDS-Related Dementia - Antiretrovirals can potentially alter neuropathogenesis of cognitive disorders

HIV/AIDS-Related Infection - Intramedullary tuberculoma mimicked primary CNS lymphoma in AIDS patient

HIV/AIDS-Related Infection - Novel sequevar of M. flavescens isolated from synovial fluid of AIDS patient