Protein Signaling
Transcriptional activity of Smad proteins in development monitored in vivo
Published in Blood Weekly, January 20th, 2005
"Signaling by bone morphogenetic proteins is essential for a wide variety of developmental processes. Receptor-regulated Smad proteins, Smads 1 and 5, are intracellular mediators of bone morphogenetic protein signaling.
"Together with Smad4, these proteins translocate to the nucleus and modulate transcription by binding to specific sequences on the promoters of target genes," researchers in the Netherlands report.
"We sought to map transcriptional Smad1/5 activity in development by generating embryonic stem cell lines carrying a Smad1/5-specific...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Blood Weekly
Source: Blood Weekly (2005-01-20)
More Articles from Blood Weekly
- Embryonic Stem Cell Research
Genes identified that are enriched in embryonic stem cells - Neural Stem Cell Transplantation
Neural SCT promotes long-term functional recovery after traumatic brain injury - Tissue Engineering
Cartilage-like tissue engineered with mesenchymal SCs and silk protein scaffolds - Wound Healing
BM-derived cells contribute to epithelial engraftment during wound healing - Antiretroviral Therapy
Drug-dependent HIV-1 variant emerges during T20 fusion inhibitor therapy - Antiretroviral Therapy
Novel sesterterpenes isolated from Madagascan sponges inhibit HIV-1 RT - More from this issue of Blood Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
