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Wound Healing

BM-derived cells contribute to epithelial engraftment during wound healing

Published in Blood Weekly, January 20th, 2005

Bone marrow-derived cells contribute to epithelial engraftment during wound healing

"Recent findings suggest that bone marrow-derived cells (BMDC) may contribute to tissue maintenance throughout the body. However, it is not yet known whether marrow-derived epithelial cells are capable of undergoing proliferation.

"Our laboratory has shown that BMDC engraft as keratinocytes in the skin at low levels (less than or equal to 1%) in the absence of injury. Here we show that skin damage affects the degree of engraftment of BMDC as keratinocytes and that the keratinocytes are actively cycling," scientists in the United States report.

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