Blood Weekly
Susan Hasty, Publisher
Table of Contents . . . February 3rd, 2005
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Blood Weekly | Other Publications
Blood Substitute - HBOC-based hemoglobin substitutes important tool for peri-operative anemia
Bone Marrow Transplantation - Genetic polymorphisms predict outcome of bone marrow transplants
Liver Regeneration - Intact signaling by TGF-beta not required for termination of liver regeneration
Stem Cell Transplantation - Haploidentical mismatched SCT is viable alternative for acute leukemia treatment
Tissue Engineering - Chitosan-gelatin complex scaffolds used for cartilage tissue engineering
Adenovirus - Adenovirus protein E4orf6 interaction mediated by BC-box motif
Adenovirus & Coxsackievirus - Coxsackievirus/adenovirus receptor interacts with MUPP-1 within tight junction
Allergy & Immunology - LIR3 counter-regulatory for both adaptive and innate receptors
Angiology - Cells with hemangioblastic potential could treat several human diseases
Anticoagulant - Effects of daily vitamin K replacement upon warfarin therapy reviewed
Antimalarial & Anticancer Drug - Madagascan plant extracts have antiplasmodial and antileukemic activity
Antimicrobials - Algal strains antibacterial against Gram-positive/negative bacteria
Antimicrobials - Link between beta-defensin tertiary structure and antimicrobial activity
Apoptosis - Apoptosis induced in regenerating liver after partial hepatectomy
Apoptosis - Clusterin overexpression in prostate cells induces apoptosis
Apoptosis - TNF-alpha modulates pro-apoptotic gene expression
Apoptosis - bFGF-induced apoptosis effected through p38(MAPK) activation
Asthma - Asthma susceptibility genes may point to new pathway in asthma pathogenesis
Bacteremia - Bacteremia caused by Sedimentibacter hongkongensis sp nov in cancer patient
Bacterial Pathogenesis - Bacteria binding by DMBT1/SAG/gp-340 confined to VEVLXXXXW motif in CRCR domains
Bacteriology - Thioredoxin reductase alters cytolytic activity of antibacterial peptide
Beta-Lactam Antibiotics - beta-lactam impact on VRE colonization related to colonizing strain
Bioengineering - Cord blood stem cell banks purchase record number of bioarchiving systems in Q2
Bioengineering - Engineered grafts could produce adenosine for therapeutic use
Bioengineering - Genetically modified progenitor cells augment therapeutic angiogenesis
Bioengineering - IND filed for human neural stem cell transplant treatment for Batten Disease
Bioengineering - Scientists fail to establish consensus on defining a stem cell, continue debate
Biotechnology - Systematic multiplex RT-PCR developed for cDNA expression analysis
Blood Supply - National blood group urges people to volunteer and donate blood regularly
Bone - Calcium and calcitriol prophylaxis attenuates post-transplant bone loss
Bone Marrow Transplantation - IL-18 has paradoxical effects on CD4 and CD8 cell-mediated GVHD
Business Update - America's Blood Centers awards 3-year contract for protective medical devices
Business Update - Companies sign development agreement for BioFoam
Cancer Therapy - Therapy directed against Bcl-2 helps rituximab limit lymphoma growth
Cell Signaling - Myeloid cell GPI-anchor deficiency causes impaired Fc gamma R effector functions
Cell Signaling - Recombinant murine Wnt-1 induces intracellular signaling of Wnt pathway
Chronic Myeloid Leukemia - Real-time qPCR screens imatinib-treated CML patients for BCR-ABL mutations
Cigarette Smoke - Cigarette smoke-induced DNA damage is reversible
Clinical Trials - Company updates safety committee review, red blood cell system clinical trial
Collaborations - Contract signed with America's Blood Centers for disease testing
Colon Cancer - PBR ligand-triggered signaling pathways lead to cell cycle arrest
Colorectal Cancer - TS genotype independent predictor of survival in colorectal cancer patients
Cryptococcosis - Pleural cryptococcosis associated with idiopathic CD4 positive T-lymphocytopenia
DNA Amplification - DNA amplification method tolerant to sample degradation
DNA Repair - DNA damage repair slower in individuals with Ser/Cys or Cys/Cys OGG1 genotypes
Diagnostics - Gen-Probe licenses tests for markers of genitourinary and other cancers
Diagnostics - Target-capture polymerase chain reaction measures hepatitis B load accurately
Disease Associations - Study of South Koreans suggests diabetes-cancer link
Embryonic Stem Cell Research - Functional neurons generated by directed differentiation from ESCs
Embryonic Stem Cell Research - Phosphoinositide 3-kinase-dependent signaling regulates ESC self-renewal
Embryonic Stem Cell Research - mTOR gene disruption prohibits embryonic stem cell development
Environmental Health - EPA seeking review on potential health risks of chemical used in Teflon
Epidemics - Pathogen spillover occurs when epidemics are driven by reservoir transmission
Ethics - Conservative objections to embryonic stem cell research rebutted
Ethics - Ethical reasoning and institutional process traditions shape UK SC research
Forensic Science - DNA amplified from tissues exposed to various environments via competitive PCR
Free Radical Formation - Fifty-hertz magnetic fields induce free radical formation in BM-derived cells
Fusarial Infection - Hospitals may be reservoirs for nosocomial fusarial infections
Garlic - Organosulfur compounds in garlic may alter chemotherapeutic treatments
Gene Mutation - HPRT mutant frequency increased at higher rate in smokers than in nonsmokers
Gene Transfer - Phi C31 integrase and nucleofection create stable transgene expression
Graft-versus-Host Disease - Company announces top-line results of pivotal trial of orBec
HHV-8 Diagnostics - Latent/lytic HHV-8 transcripts detected/quantitated via Rnase Protection Assay
HIV/AIDS Complications - Potential cure for lymphoma in HIV patients
HIV/AIDS Pathogenesis - Glutamine-rich region of HIV-1 Tat is involved in T-cell apoptosis
HIV/AIDS Pathogenesis - HIV-1 Nef hydrophobic pocket critical to Hck recruitment and activation
HIV/AIDS Pathogenesis - HIV-specific T cells less differentiated early in infection in rapid progressors
HIV/AIDS Pathogenesis - No correlation between HIV viral load in semen/blood and systemic CD8 response
HIV/AIDS Pathogenesis - Women with cervicovaginal ADCC have lower genital HIV-1 RNA loads
HIV/AIDS Research - Cellular cofactors for HIV replication identified via ribozyme-based genomics
HIV/AIDS Research - Evidence found for positive epistasis in HIV-1
HIV/AIDS Research - PBMC viral rebound after HAART cessation predicted by HIV Nef transcript level
HIV/AIDS Therapy - DL-amino acid-containing fusion peptide inhibits cell-cell fusion
HIV/AIDS Therapy - IVDU impairs CD4 cell recovery in patients initiating successful HAART
HIV/AIDS Therapy - Lopinavir plasma concentrations higher when combined with valproic acid
HIV/AIDS Therapy - T-1249 efficiency related to ability to insert/adsorb to lipidic bilayers
HIV/AIDS-Associated Disease - HHV8+ plasmablasts within lymphoid follicles/BM are features of early MCD
HIV/AIDS-Related Infection - Disseminated M. avium associated with somatotropic axis disruption in AIDS
Hematology - Aberrant hypermethylation associates with gene silencing in Burkitt lymphoma
Hematology - CRD-BP knockdown promotes leukemia cell proliferation
Hematology - Hepatitis E virus markers abound in hemodialysis patients in Greece
Hemophilia A - Megakaryocytes produce bioactive factor VIII after transfection
Hepatitis C Virus - Study predicts prevalence of hepatitis C in Texas
Hereditary Hemorrhagic Telangiectasia - Health-related quality of life in a rare disease analyzed
Immunology - Reengineered stromal cells support the proliferation of naive T cells
Ischemia - Several enzyme systems are responsible for increased production of superoxide
Lactation - Mammary epithelial cell number/activity determining factors for milk production
Legal Issues - Curative announces settlement with California Department of Health Services
Malaria Treatment - Protease inhibitors inhibit Plasmodium falciparum
Marine Aspergillus - Increased host resistance drives decline in marine aspergillosis
Megakaryocytopoiesis - VWF sensitive and distinctive marker for early (2N and 4N) megakaryocytes
Melanoma Risks - Exposure to sunlamps and welding predicts risk of choroids/ciliary body melanoma
Menorrhagia - Underlying bleeding disorders frequently present in women with menorrhagia
Multiple Myeloma - Early paraprotein response identifies high risk multiple myeloma patients
Multiple Myeloma - Multiple myeloma pain treatment clinical trial initiated
Neural Stem Cell Research - NSCs play critical role in repairing axonal injury in the adult spinal cord
Non-Hodgkin Lymphoma - Sun exposure may protect against non-Hodgkin lymphoma
Nosocomial Infections - Medical procedures and transfusions transmit hepatitis C infections in Poland
Obstetric Anesthesia - Case reported of amniotic fluid embolism during cesarean section
Obstetrics - New findings in the area of obstetrics detailed
Occupational Health - Nurses in Turkey are exposed to bloodborne pathogens through sharps injuries
Oncology - Nonmyeloablative stem cell allografting effective as salvage therapy
Pancreatic Fibrosis - Pressure activates pancreatic stellate cells
Personnel - Biopharmaceutical company creates clinical board, signs stem cell agreement
Personnel - Former governor James Greenwood assumes presidency of biotechnology association
Plant Parasite - Host-parasite coevolutionary conflict between Arabidopsis and downy mildew
Prostate Cancer - EGCG from green tea is a natural inhibitor of prostate carcinoma aggressiveness
Reperfusion Injury - Activation of caspases during reperfusion may protect against ischemic injury
Salmon Infection - Chlamydia-like bacterium identified in farmed Atlantic salmon
Sour Gas Exposure - GSTM1/T1 polymorphisms modulate blood changes associated with sour gas exposure
Spotted Fever - Spotted fever group rickettsiae characterized from flea and tick specimens
Stem Cell Research - BM CD34+ SCs mature on stromal cell line without thymus microenvironment
Stem Cell Research - BMP-2 silk fibroin films induce BM stromal cell osteogenic differentiation
Stem Cell Research - CD34+ umbilical cord blood cells are rich fractions in hepatic progenitor cells
Stem Cell Research - Caspase-9 inhibitor enhances stress-induced apoptosis in B-lineage cells
Stem Cell Research - Cytoskeletal organization of MSC changes during osteogenic differentiation
Stem Cell Research - IL-6 directly stimulates oval cells
Stem Cell Research - JunB deficiency leads to myeloproliferative disorder arising from HSCs
Stem Cell Research - NFATc2 (NFAT1) expressed at high levels in CD34+ cells and megakaryocytes
Stem Cell Research - Nodal inhibits differentiation of ESC along neuroectodermal default pathway
Stem Cell Research - Proposals suggested for overcoming rejection of embryonic stem cell derivatives
Stem Cell Research - Radiation-induced HSC apoptosis associated with ROS/intracellular pH alterations
Stem Cell Research - Review examines agents and detectors for stem cell tracking during trials
Stem Cell Research - Thrombospondin-4 C-terminal peptide stimulates erythroid cell proliferation
Stem Cell Research - Wnt/beta-catenin signaling pathway has role in ESC differentiation
Stem Cell Transplantation - ASCT for lysosomal and peroxisomal metabolic disease treatment is robust
Stem Cell Transplantation - Advances in HSCT offers better treatments for hematological malignancies
Stem Cell Transplantation - Autologous/syngeneic stem cell transplantation treats refractory GvHD
Stem Cell Transplantation - Leukemia-free survival and relapse similar in unrelated cord blood/BM transplant
Stem Cells Research - Alginate bead culture system differentiates MSC into articular chondrocytes
Stem Cells Research - Epidermal stem cells isolated by adherence offers route to clinical application
Stem Cells Transplantation - HSC transplantation can induce tolerance to organ allografts
Surgical Technology - Pharma company completes regulatory dossier for blunt trauma coagulation factor
Thalassemia - Hemoglobin-stabilizing protein role in erythropoiesis and thalassemia revealed
Thymus Tuberculosis - Primary thymus TB patient responded poorly to anti-mycobacterial therapy
Tissue Regeneration - Deer antler regeneration may be a stem cell-based process
Toxicology - Blood lead levels of mothers and newborns assessed in middle China
Transplant Medicine - Blood pressure control in kidney transplantation has therapeutic implications
Transplant Medicine - First patient dosed in clinical trial for ATG-Fresenius S
Transplant Medicine - The angiogenesis inhibitor TNP-470 attenuates cardiac allograft vasculopathy
Transplant Medicine - Underlying liver disease complicates liver cancer-related transplantation
Tumor Suppression - ARF impedes NPM/B23 shuttling in Mdm2-sensitive tumor suppressor pathway
Ulcerative Colitis - Refractory ulcerative colitis susceptibility associated with hMLH1 polymorphism
Virology - First analysis shown of HIV-1 RNA structure in infected cells and in virions
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